83 years of age, Professor Angst still takes more than a keen interest in research into mood disorders and in particular is actively engaged in analysing the data collected from an epidemiological cohort he began to observe more than 30 years ago.1 Furthermore, he still does not shy away from questioning perceived wisdom when data he and his colleagues have collected point to a different conclu...

BACKGROUND Existing literature on mood disorders suggests that the demographic distribution of bipolar disorder may differ from that of unipolar depression, and also that bipolar disorder may be especially disruptive to personal functioning. Yet, few studies have directly compared the populations with unipolar depressive and bipolar disorders, whether in terms of demographic characteristics or ...

A significant overlap between childhood mood disorders and many aspects of attention deficit hyperactivity disorder (ADHD) has been established. High rates of co-occurrence, familial aggregation, and more severe clinical manifestations of the illnesses when they are comorbid suggest that common genetic and environmental factors may contribute to the development of both disorders. Research on th...

Background and Purpose: The aim of this study was to investigate the role of borderline personality disorder (BPD) characteristics as a predictor of suicidal in patients with bipolar disorder. Method:  This research was a cross-sectional study and the people who were selected were 50 (25 women, 25 men) who were hospitalized in Shahid Beheshti hospital. They had referred to the psychiatrists an...

Not only is bipolar disorder a chronic, severe psychiatric disorder, it is also expensive to treat and expensive to society. An estimate of the total cost of bipolar disorder made more than a decade ago was as high as 45 billion dollars per year. Most of this cost is accounted for by indirect costs related to reduced functional capacity and lost work. Patients with bipolar disorder have higher ...

BACKGROUND There is a need for better understanding and research of the comorbidity structure in schizophrenia and bipolar disorder. OBJECTIVE To assess the prevalence of somatic and psychiatric comorbidity in schizophrenia and bipolar affective disorder treated at the University Hospital Centre Zagreb. METHOD This retrospective study compares the prevalence of comorbid diagnosis of somatic...

Affective disorders have hitherto been explained in terms of neurotransmitter deficits or dysfunction. However, research in patients with bipolar disorder shows that, while neurotransmitter dysfunction is clearly important in the presentation of bipolar disorder, it is not the sole explanation for its etiology. Rather than all of the neurotransmitters being independently abnormal in bipolar dis...