Tenocytes express primary cilia, which elongate when tendon is maintained in the absence of biomechanical load. Previous work indicates differences in the morphology and metabolism of the tenocytes in the tendon fascicular matrix (FM) and the inter-fascicular matrix (IFM). This study tests the hypothesis that primary cilia in these two regions respond differently to stress deprivation and that ...

Physics-based models of human locomotion potentially provides a useful tool for full body biomechanical analysis, provides insights into equipment designs as well as for the study of man-machine interactions. To enable such model to be used in biomechanical analysis, proper capture and input of human motion data as well as modelling parameter is needed to ensure meaningful and reliable results ...

The purpose of this study was to use regularised regression models identify the most important biomechanical predictors throwing distance in elite male (M) and female (F) javelin throwers at 2017 IAAF world championships. Biomechanical data from 13 12 who competed championships were obtained an official scientific report. Regularised used investigate associations between release parameters, who...

Objective- Tendon healing, in terms of histologic and functional characteristics, is always inferior to its normal level due to the poor vascularity and low metabolic rate. Curcumin possesses anti-inflammatory, anti-oxidant and healing effects. This study aimed to investigate effects of curcumin on Achilles tendon experimental injury using histopathology, biomechanical and functional evaluation...

INTRODUCTION: Usually, predefined kinematic parameters are investigated in biomechanical studies of human motion. In recent years, techniques of machine learning have been added to this field of research (Chau, 2001). In this study different dimension reduction methods like Principal Component Analysis (PCA) and Fourier Transformation (FT) are investigated as an alternative to common biomechani...

Background Diabetic peripheral neuropathy (DPN) affects the sensory, motor, and autonomic nervous system. The biomechanical changes resulting from DPN may translate to increased plantar pressures in the foot, which contributes to the pathogenesis and development of foot ulcers. This review aims to investigate the existing biomechanical literature associated with gait, dynamic electromyography a...

Quadriceps tendon ruptures disrupt the extensor mechanism of the knee and require urgent surgical management. Traditional repair techniques have had mixed biomechanical and clinical results risking weakness and extensor lag. We describe a novel technique using tape suture and knotless anchors, which has performed superiorly during biomechanical testing and yielded terrific early clinical results.

Although biomechanical signals generated during joint mobilization are vital in maintaining integrity of inflamed cartilage, the molecular mechanisms of their actions are little understood. In an experimental model of arthritis, we demonstrate that biomechanical signals are potent anti-inflammatory signals that repress transcriptional activation of proinflammatory genes and augment expression o...