نتایج جستجو برای: biofunctionalization

تعداد نتایج: 250  

Journal: :Physical chemistry chemical physics : PCCP 2013
Debasmita Ghosh Somrita Mondal Chandra Nath Roy Abhijit Saha

Semiconductor nanomaterials have found numerous applications in optoelectronic device fabrication and in platforms for drug delivery and hyperthermia cancer treatment, and in various other biomedical fields because of their high photochemical stability and size-tunable photoluminescence (PL). However, little attention has been paid to exploring the energetics of formation of these semiconductor...

Journal: :Lab on a chip 2012
Daphné Duval Ana Belén González-Guerrero Stefania Dante Johann Osmond Rosa Monge Luis J Fernández Kirill E Zinoviev Carlos Domínguez Laura M Lechuga

One of the main limitations for achieving truly lab-on-a-chip (LOC) devices for point-of-care diagnosis is the incorporation of the "on-chip" detection. Indeed, most of the state-of-the-art LOC devices usually require complex read-out instrumentation, losing the main advantages of portability and simplicity. In this context, we present our last advances towards the achievement of a portable and...

2010
D. Regatos A. Calle D. Fariña A. Cebollada G. Armelles B. Sepúlveda L. M. Lechuga

We present the optimization of a new material structure used as transducer in a MagnetoOptical Surface Plasmon Resonance (MOSPR) biosensor. The MOSPR sensor is a modification of the standard Surface Plasmon Resonance (SPR) biosensor, which arises from the introduction of a ferromagnetic metal layer with Magneto-Optical (MO) activity together with the usual gold layer of SPR biosensors. Such com...

2014
María Soler M.-Carmen Estevez Mar Alvarez Marinus A. Otte Borja Sepulveda Laura M. Lechuga

Design of an optimal surface biofunctionalization still remains an important challenge for the application of biosensors in clinical practice and therapeutic follow-up. Optical biosensors offer real-time monitoring and highly sensitive label-free analysis, along with great potential to be transferred to portable devices. When applied in direct immunoassays, their analytical features depend stro...

Journal: :Ultramicroscopy 2009
C Lamprecht J Danzberger P Lukanov C-M Tîlmaciu A-M Galibert B Soula E Flahaut H J Gruber P Hinterdorfer A Ebner F Kienberger

We present a comparative study of several non-covalent approaches to disperse, debundle and non-covalently functionalize double-walled carbon nanotubes (DWNTs). We investigated the ability of bovine serum albumin (BSA), phospholipids grafted onto amine-terminated polyethylene glycol (PL-PEG(2000)-NH(2)), as well as a combination thereof, to coat purified DWNTs. Topographical imaging with the at...

Journal: :ACS applied materials & interfaces 2015
Antonio Francesko Lucas Blandón Mario Vázquez Petya Petkova Jordi Morató Annett Pfeifer Thomas Heinze Ernest Mendoza Tzanko Tzanov

Laccase-assisted assembling of hybrid biopolymer-silver nanoparticles and cork matrices into an antimicrobial material with potential for water remediation is herein described. Amino-functional biopolymers were first used as doping agents to stabilize concentrated colloidal dispersions of silver nanoparticles (AgNP), additionally providing the particles with functionalities for covalent immobil...

Journal: :Nature nanotechnology 2009
Nan Ma Edward H Sargent Shana O Kelley

Colloidal semiconductor nanocrystals are widely used as lumiphores in biological imaging because their luminescence is both strong and stable, and because they can be biofunctionalized. During synthesis, nanocrystals are typically passivated with hydrophobic organic ligands, so it is then necessary either to replace these ligands or encapsulate the nanocrystals with hydrophilic moieties to make...

2017
Xiaotong Ye Sander Leeflang Chengtie Wu Jiang Chang Jie Zhou Zhiguang Huan

Porous Ti-6Al-4V scaffolds fabricated by means of selective laser melting (SLM), having controllable geometrical features and preferable mechanical properties, have been developed as a class of biomaterials that hold promising potential for bone repair. However, the inherent bio-inertness of the Ti-6Al-4V alloy as the matrix of the scaffolds results in a lack in the ability to stimulate bone in...

2016
Ville Hynninen Leena Vuori Markku Hannula Kosti Tapio Kimmo Lahtonen Tommi Isoniemi Elina Lehtonen Mika Hirsimäki J. Jussi Toppari Mika Valden Vesa P. Hytönen

A straightforward solution-based method to modify the biofunctionality of stainless steel (SS) using heterobifunctional silane-polyethylene glycol (silane-PEG) overlayers is reported. Reduced nonspecific biofouling of both proteins and bacteria onto SS and further selective biofunctionalization of the modified surface were achieved. According to photoelectron spectroscopy analyses, the silane-P...

Journal: :Lab on a chip 2008
Xiaolong Luo Angela T Lewandowski Hyunmin Yi Gregory F Payne Reza Ghodssi William E Bentley Gary W Rubloff

We report a biofunctionalization strategy for the assembly of catalytically active enzymes within a completely packaged bioMEMS device, through the programmed generation of electrical signals at spatially and temporally defined sites. The enzyme of a bacterial metabolic pathway, S-adenosylhomocysteine nucleosidase (Pfs), is genetically fused with a pentatyrosine "pro-tag" at its C-terminus. Sig...

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