نتایج جستجو برای: biochemical mechanism

تعداد نتایج: 687990  

2011
Craig T. Jordan Richard I. Fisher

Melampomagnolide B has been identified as a new antileukemic sesequiterpene. A biotin-conjugated derivative of melampomagnolide B was designed and synthesized in order to elucidate its mechanism of action. A study of the biochemical interactionsof the biotin probe suggests that malampomagnolide B derives its remarkable selectivity for leukemic cells over normal hematopoietic cells from its ...

2009
Andrea R Yoder Matthew D Stone Tim Griffin Lincoln R Potter

Background While it has long been know that phosphorylation of the kinase homology domain is a key regulatory mechanism of natriuretic peptide receptors, no biochemical proof for individual phosphorylation sites has been reported. Here, we describe biochemical verification of previously identified phosphorylation sites in both natriuretic peptide receptor A (NPR-A) and natriuretic peptide recep...

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