OBJECTIVE To study and establish sex hormone cutoff levels for osteoporosis risk in men over 50 years old. METHODS Case-control study of 216 men > 50 years, 110 with osteoporosis (O) and 106 with normal bone density (C). We measured estradiol (E2), sex hormone binding globulin (SHBG), total testosterone (TT) and albumin. Free testosterone (FT) and bioavailable testosterone (BT) were calculate...

INTRODUCTION Statins belong to the most commonly used medicines worldwide. They affect cholesterol synthesis and thus they may suppress steroidogenesis. Our aim was to evaluate whether the use of statins is associated with the concentration of sex hormones.Material and methods/Results: In a population sample of men (n = 237) we found that subjects receiving statins had significantly lower conce...

An experiment was conducted to examine how potential phosphorus (P) bioavailability (inferred from speciation) differs in feed and feces collected in spring from four dairy herds representing different management systems: (i) total confinement with cows fed total mixed ration (TMR), (ii) total confinement with TMR plus P mineral supplement, (iii) a hybrid of confinement with TMR and pastoral gr...

Soils in the Lower Swansea Valley, (United Kingdom) contain elevated level of metals, enough to cause direct or indirect effects on human health. This study assesses severity soil pollution and bioavailability Cu other metals (Ni, Zn, Co, Pb Cr) soils with various distances from a Ni refinery. We compare concentrations operationally defined fractions (bioavailable, bound Fe/Mn oxide incorporate...

Colloids and nanoparticles leached from agricultural land are major carriers of potentially bioavailable nutrients with high mobility in the environment. Despite significant research efforts, accurate knowledge macronutrients colloids is limited. We used multi-elemental synchrotron X-ray fluorescence (XRF) microscopy multivariate spatial analysis atomic absorption near-edge structure (XANES) sp...

and Implications The dietary bioavailable riboflavin needs for body maintenance and body protein and fat accretion were estimated in pigs. The riboflavin required to support body protein accretion was higher than that for body maintenance or fat accretion. Specifically, the riboflavin required to support protein accretion was six times higher than the riboflavin required to support fat accretio...

BACKGROUND Studies have shown altered vitamin D metabolism in obesity. We assessed differences between obese and normal-weight subjects in total, free, and bioavailable 25-hydroxyvitamin D (25(OH)D, 25(OH)DFree, and 25(OH)DBio, respectively), vitamin D binding protein (DBP), parathyroid hormone (PTH) and bone traits. METHODS 595 37-47-year-old healthy Finnish men and women stratified by BMI w...

Nitrogenase catalyzes a key step in the global nitrogen cycle, the nucleotide-dependent reduction of atmospheric dinitrogen to bioavailable ammonia. There is a substantial amount of interest in elucidating the biosynthetic mechanisms of the FeMoco and the P-cluster of nitrogenase, because these clusters are not only biologically important but also chemically unprecedented. In this review, we su...