As a teenager in a South Dakota hamlet (Pierpont, population 326 in the 1940 census) I had no idea that I would become a scientist. The only formal science course my tiny high school (40 students in four grades, taught by three teachers) offered was physics, taught by the sports coach (a history major) and featuring the ‘‘dissection’’ of a 1928 Overland (teacher: ‘‘I have been told that the mod...

Tissue Engineering is a rapidly growing field with novel scientific concepts, new technological methods, and evolving regulatory policies for clinical translation. Most of the current basic regulations are taken from the pharma, bio-pharma, cell therapy with little modifications, and new inclusion for development of regulatory frame work for advanced therapeutic products. We propose to highligh...

The paper focuses on bio®lms subject to turbulent ̄ow and high liquid velocity (of the order of 1 m s) which can be found in heat exchangers, water distribution systems and in some wastewater reactors. An overall model describing bio®lm development is presented, which includes the effects of biomass detachment due to the hydrodynamic forces. A methodology for estimating substrate consumption fr...

COURSE DESCRIPTION: The course is designed for graduate students in biology wanting to aquire a more detailed working knowledge and appreciation of mammalian diversity in structure, function, ethology, and ecology. Knowledge and skills aquired in this course will be useful to field and laboratory studies in ecology, evolution, animal behavior, biogeography, wildlife management, and related disc...

Abstract Background Upadacitinib (UPA) and tofacitinib (TOFA) are Janus kinase (JAK) inhibitors approved for the treatment of patients (pts) with moderately to severely active ulcerative colitis (UC), but evidence on their comparative efficacy safety is limited. This study conducted a placebo (PBO)-anchored matching-adjusted indirect comparison (MAIC) induction outcomes between UPA TOFA. Method...

Unit of Otolaryngology University Campus Bio-Medico, Rome, Italy Unit of Cardiovascular Science, University Campus Bio-Medico, Rome, Italy Unit of Cardiovascular Science, University Campus Bio-Medico, Rome, Italy Unit of Otolaryngology, University Campus Bio-Medico, Rome, Italy Unit of Otolaryngology, University Campus Bio-Medico, Rome, Italy Unit of Otolaryngology, University Campus Bio-Medico...

background: several grafting materials have been used for alveolar ridge augmentation. the literature lacks researches to compare cenobone to other grafting materials. the aim of this study was to compare cenobone/cenomembrane complex to bio-oss/bio-gide complex in lateral alveolar bone augmentation in terms of radiographic, histologic, and histomorphometric parameters. materials and methods: i...

Preliminary work on the development of measures appropriate for the safety domain is reported. Measures are expressed in the style of the Practical Software and Systems Measurement (PSM) approach, a programme sponsored by the US DoD. Proposed measures are integrated with the PSM measurement framework. Reported work has been informed by discussions within the PSM community and by concurrent work...