To cite: Marques NS, Miranda A, Barros S, et al. BMJ Case Rep Published online: [please include Day Month Year] doi:10.1136/ bcr-2015-213651 DESCRIPTION A 29-year-old woman with a history of renal cysts, hypertension and lymphoedema-distichiasis syndrome, was referred to ophthalmology, with bilateral blurred vision, hyperaemia and ocular pain, developed over months. The patient had no positive ...

Background: A prospective, interventional, comparative study carried out in rural population of northern India in western UP. Fungal keratitis studies available in literature were also reviewed. Methods: Patients presenting in eye OPD of UPRIMS & R Saifai, Etawah, UP with suspected microbial keratitis were recruited to the study. Corneal ulceration was defined as loss of corneal epithelium with...

BACKGROUND The purpose of this study was to evaluate the antimicrobial activity of two nitric oxide donors, ie, S-nitrosoglutathione (GSNO) and S-nitroso-N-acetylcysteine (SNAC), against clinical isolates from patients with infectious keratitis. METHODS Reference broth microdilution assays were performed to determine the minimum inhibitory and bactericidal concentrations for GSNO and SNAC aga...

PURPOSE This study aimed to determine the effect of salicylic acid on the membrane proteome, sensitivity to antibiotics, and production of microbial keratitis by Pseudomonas aeruginosa. METHODS P. aeruginosa 6294 was grown in the presence or absence of 30 mM salicylic acid. Bacterial membrane proteins were extracted in carbonate buffer, separated using two-dimensional gel electrophoresis and ...

PURPOSE To report a case of varicella-zoster virus (VZV) keratitis with detection of VZV DNA in the tear fluid of not only the symptomatic eye but also the contralateral asymptomatic eye by polymerase chain reaction (PCR). METHODS This is a case report. A 63-year-old otherwise healthy woman presented with circular corneal ulcer and stromal opacity with infiltration accompanied by mild conjunc...

As early as 1930 herpes simplex keratitis was considered to be the most important specific keratitis in the United States (Gundersen, I936; Thygeson, 1953). This statement is true today, not only for the United States but for all other countries outside the tropical and subtropical zones having a high standard of hygiene and medical care. With the advent of local steroid medication in the treat...

Contact lens wearers are at great risk of developing microbial keratitis because of incorrect usages and unhygienic maintenance of contact lenses. Therefore, the present study was planned to provide data that will be helpful in selecting the anti-microbial to cure microbial keratitis. One hundred bacterial isolates from conjunctiva of contact lenses wearer were isolated, identified and subjecte...