BACKGROUND The caspase-associated recruitment domain-containing protein (CARP) is expressed in almost all tissues. Recently, the tumor-suppressive function of CARP was discovered and attracted increasing attention. This study aimed to investigate the role of CARP in the carcinogenesis of human gastric carcinoma. METHODOLOGY/PRINCIPAL FINDINGS Compared with normal gastric tissue, the downregul...

The aim of this study was to investigate the genetic mechanism of the transparent trait in transparent crucian carp. We observed body color development in transparent crucian carp larvae and analyzed heredity of color in hybrids produced with red crucian carp, ornamental carp, and red purse carp. The results showed that the body color of the newly hatched larvae matured into the adult pattern a...

BACKGROUND Single nucleotide polymorphisms (SNPs) have been used as genetic marker for genome-wide association studies in many species. Gene-associated SNPs could offer sufficient coverage in trait related research and further more could themselves be causative SNPs for traits. Common carp (Cyprinus carpio) is one of the most important aquaculture species in the world accounting for nearly 14% ...

The varieties of carp we mentioned before are all hybrids. The traits of the offspring of the hybrid carps will be segregated. So new hybrids should be made every year and at least two varieties of parental fish must be conserved in order to obtain the hybrid carps. This can be inconvenient in practice. Jian carp is the first variety of common carp that was produced by artificial breeding in Ch...

Pymatuning Lake, located on the Pennsylvania/Ohio border, is noted for the large numbers of bread-eating carp that frequent the Linesville Causeway "carp bowl" from May to November. Carp were trapped in 1952 and 1984 at the carp bowl, tagged, and relocated varying distances away from the bowl in Sanctuary, Middle, and Lower lakes. Carp traversed the return distances of up to 9 km in less than 4...

Goal. The study aimed to analyze and assess the genetic variability of different age groups silver bighead carps by polymorphism protein enzyme systems.
 Methods. Blood samples were taken from (Hypophthalmichthys molitrix) (Aristichthys nobilis) "Sunpoint Ukraine" LLC, Slobozhanske, Zmiiv district, Kharkiv region.
 tail vein was collected age-2 age-3 fish in vivo placed into tubes wit...

Doxorubicin (Adriamycin) is an effective anti-cancer drug, but its clinical usage is limited by a dose-dependent cardiotoxicity characterized by widespread sarcomere disarray and loss of myofilaments. Cardiac ankyrin repeat protein (CARP, ANKRD1) is a transcriptional regulatory protein that is extremely susceptible to doxorubicin; however, the mechanism(s) of doxorubicin-induced CARP depletion ...