The proinflammatory stimulus of chorioamnionitis is commonly associated with preterm delivery. Women at risk of preterm delivery receive antenatal glucocorticoids to functionally mature the fetal lung. However, the effects of the combined exposures of chorioamnionitis and antenatal glucocorticoids on the fetus are poorly understood. Time-mated ewes with singleton fetuses received an intra-amnio...

Celestona (betamethasone-disodiumphosphate) and Celeston (betamethasone-acetat + betamethasone-disodiumphosphate) given intramuscularly to pregnant women in order to reduce the frequency of respiratory distress syndrome does not reduce the occipitofrontal circumference of the newborn infants. Before the results from the actual work were available an impeding effect of the evolution of the brain...

Thirty-nine patients took part in a double-blind, between-patient clinical trial to compare clobetasone butyrate, betamethasone phosphate, and placebo eye drops in the treatment of episcleritis. Although from the symptom scores the patients given placebo appeared to do as well as the other patients in the first week of treatment, they did significantly less well after this time. Clobetasone but...

OBJECTIVE During the last decades, management of intertriginous psoriasis (IP) has been unsatisfactory because of the adverse effects associated with long-term corticosteroid application and the lack of alternatives. Recently, both pimecrolimus and tacrolimus have been investigated for this indication and shown to be safe and effective. So far, to our knowledge, a comparison of one of these dru...

Objective: Treatment of a recalcitrant case of Kimura’s disease (KD) is described. Lesions recurred after injection of betamethasone, but responded well to radiation therapy using a Varian 21EX linear accelerator. A literature review and discussion of efficiency and safety issues is included. Method: A 53-year-old female with KD of the right cheek was treated with intramuscular injection of bet...

Objectives: This study was undertaken to compare the efficacy and safety of fexofenadine with chlorpheniramine and betamethasone in allergic rhinitis. Methods: This was a prospective observational study on 75 patients of allergic rhinitis. They were randomly divided into 3 groups of 25 patients each for receiving fexofenadine, chlorpheniramine and betamethasone respectively. Improvement of symp...

Salah satu tanaman yang mempunyai nilai ekonomis tinggi yaitu rosemary (Rosemarinus officinalis L.). Tanaman ini aroma dan rasa khas banyak mengandung senyawa dapat dimanfaatkan sebagai antioksidan, antijamur, antivirus, antibakteri, antitumor, antitrombotik, antidepresan. Pemanfaatan terutama ekstrak daunnya dilakukan dengan terlebih dahulu melakukan pengujian terhadap tersebut, sehingga tujua...

Evaluation of the effects of betamethasone on patients with intrauterine growth restriction in couple with preeclampsia is not well studied. This study was designed to assess and compare the changes of Doppler flow in maternal, fetal and placental arteries in singleton pregnancies complicated by IUGR and preeclampsia which are at 24-34 weeks of gestation after betamethasone therapy. This prospe...

The effects of two topical nasal preparations on human nasal ciliary beat frequency in vitro and on nasal mucociliary clearance in vivo were investigated. Betamethasone and betamethasone with neomycin drops were found to be ciliotoxic when ciliated epithelium was exposed to them in vitro, mainly owing to the effects of the preservatives benzalkonium chloride and thiomersal. The nasal mucociliar...