Dysfunction of basal ganglia is associated with the pathogenesis Parkinson's disease including alteration firing rate and excessive beta-band (13-30 Hz) synchronization activity. Neuronal heterogeneity enriches dynamics external globus pallidus (GPe), especially showing significant differences in alterations under pathological state. The precise mechanism underlying these neural signatures rema...

Abstract Introduction Smith-Magenis syndrome (SMS) is a rare disorder associated with several genetic mutations. Patients SMS experience circadian rhythm sleep-wake disorders, which may lead to significant behavioral concerns. A proposed etiology of sleep disturbances diurnal melatonin secretion. Treatment approaches aim at blocking the abnormal morning secretion and providing exogenous in even...

OBJECTIVE Despite improved perioperative management, atrial fibrillation (AF) after coronary artery bypass grafting (CABG) remains a relevant clinical problem, whose pathogenetic mechanisms remain incompletely explained. A reduced incidence of postoperative AF has been described in CABG patients receiving IV tri-iodothyronine (T3). This study was designed to define the role of thyroid metabolis...

UNLABELLED To select a movement, specific neuronal populations controlling particular features of that movement need to be activated, whereas other populations are downregulated. The selective (dis)inhibition of cortical sensorimotor populations is governed by rhythmic neural activity in the alpha (8-12 Hz) and beta (15-25 Hz) frequency range. However, it is unclear whether and how these rhythm...

Nuclear receptors (NRs) transduce environmental and metabolic signals into alterations in gene expression by recruiting coregulators that alter chromatin structure. Rev-erbs alpha and beta (NR1D1 and NR1D2, respectively) are heme receptors that comprise negative limb of the circadian clock. The Rev-erbs function in the genome by recruiting complexes containing the nuclear receptor corepressor N...

[Purpose] The purpose of the present study was to examine the effects of neurofeedback training on electroencephalogram changes in the cervical spine in adults with forward head posture through x-ray. [Subjects and Methods] The subjects of the study were 40 college students with forward head posture, randomly divided into a neurofeedback training group (NFTG, n=20) and a control group (CG, n=20...

The olfactory tubercle (OT), a trilaminar structure located in the basal forebrain of mammals, is thought to play an important role in olfaction. While evidence has accumulated regarding the contributions of the OT to odor information processing, studies exploring the role of the OT in olfaction in awake animals remain unavailable. In the present study, we begin to address this void through mul...