نتایج جستجو برای: bet v 1
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BACKGROUND Recombinant Bet v 1a (rBet v 1a) has been used in allergy research for more than three decades, including clinical application of so-called hypoallergens. Quantitative IgE binding to rBet v 1a depends on its native protein conformation, which might be compromised upon heterologous expression, purification, or mutational engineering of rBet v 1a. OBJECTIVE To correlate experimental/...
Background Lipid transfer proteins (LTP) are considered true food allergens because sensitization takes place in the gastrointestinal tract, in contrast with other food allergens like profilins or Bet v 1-homologues, where sensitization is a consequence of an allergic sensitization to inhaled allergens. Although allergy to peach LTP (pru p 3) is frequently associated to sensitization to plane t...
PURPOSE Clinical features of peanut allergy can range from localized to systemic reactions. Because peanut and birch pollen have cross-reactivity, peanut can lead to localized allergic reaction in Fagales pollen-sensitized oral allergy syndrome (OAS) patients without peanut sensitization per se. The purpose of this study was to discriminate true peanut food allergy from cross-reactive hypersens...
Five nanoporous carbons (NPCs) were prepared by polymerizing and then carbonizing carbon precursor of furfuryl alcohol accommodated in a porous metal–organic framework (MOF-5, [Zn4O(bdc)3], bdc = 1,4-benzenedicarboxylate) template. The Brunauer–Emmett– Teller (BET) surface areas for five NPC samples obtained by carbonizing at the temperatures from 530 to 1000 C fall into the range from 1140 to ...
Allergy diagnosis in Geneva area: a complex multi-ethnic community with high pan-allergen prevalence
Results 13/30, 13/21 and 6/19 were sensitized to profilin, while 14/30, 11/21 and 5/19 were positive to Bet v 1. 40% of profilin positive patients had clinical food allergy with melon or water melon. ISAC profilin results were compared at different cut-off levels with SPT to pure profilin. 11 patients were serologically profilin positive between 0.01 and 0.29 ISU ; 7 of them were SPT profilin p...
BACKGROUND Beech and oak pollen are potential allergen sources with a world-wide distribution. OBJECTIVE We aimed to characterize the allergen profile of beech and oak pollen and to study cross-reactivities with birch and grass pollen allergens. METHODS Sera from tree pollen-allergic patients with evidence for beech and oak pollen sensitization from Basel, Switzerland, (n=23) and sera from ...
t cells have been identified as key players in the pathogenesis of type 1 diabetes. however, the exact role of t-cell subpopulations in this pathway is presently unknown. the purpose of this study was to assess the expression pattern of two lineage-specifying transcription factors gata - 3 and t - bet , which are important in t helper type 1 (th1) and th2 cell development , respectively. gene e...
Preeclampsia is a leading cause of maternal and fetal morbidity/ mortality; however, the pathophysiological mechanisms are poorly understood. Vascular endothelial dysfunction in preeclampsia has been partially attributed to changes in endothelin-1 (ET-1). Several enzymes, including matrix metalloproteinases (MMPs, particularly MMP-2), cleave the inactive precursor bigET-1 (bET-1) to active ET-1...
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