During the war several English and American laboratories participated in a study of the structure and synthesis of penicillin (1, 2). In this work it was noted that when the methyl ester of benzylpenicillin (I) (see Fig. 1) was treated with mercuric chloride in ether solution and the resulting mercury derivative (II) was decomposed with hydrogen sulfide, a neutral, amorphous product was obtaine...

Benzyl chloride and tin powder were used to prepare dibenzyltin dichloride according to a literatureprocedure. In this study, IR spectroscopy, HOMO-LUMO energy gap, NBO analysis, polarizability,some geometrical parameters, natural charge and electrical potential of atoms, global hardness,electronic chemical potential, global electrophilicity index, and molar volume of dibenzyltindichloride were...

The solvolytic behavior of benzyl chloride 1 (1-chloro-1-pheny-l4,8,13,17,21pentamethyl-4,8,12,16,20-docosapentaene) revealed inconsistency in some aspects, thus the reaction mechanism is ambiguous. The ethanolysis rate (ku) of 1 is practically the same as the rate of its saturated analog (ku / ks = 2.5), indicating that the reaction may proceed by way of an unassisted process. On the other han...

The acute intravenous toxicities of a selection of three potential long-acting local anaesthetics belonging to the series of2- phenoxyethyldialkylamine were determined in mice. Two of the compounds were tertiary amines and the third a quaternary ammonium derivative.The I.V. median lethal dose, (LDso) of one of the tertiary compounds, 21A [N, N- diethyl-2- (2,6- diisopropyl) ethyl amine hyd...

Dehalococcoides ethenogenes strain 195 reductively dechlorinates tetrachloroethene (PCE) and trichloroethene (TCE) to vinyl chloride and ethene using H2 as an electron donor. PCE- and TCE-reductive dehalogenase (RD) activities were mainly membrane associated, whereas only about 20% of the hydrogenase activity was membrane associated. Experiments with methyl viologen (MV) were consistent with a ...

Indium trichloride, benzyl alcohol, and triethylamine (without an added 'directing' multidentate ligand) generate a catalyst in situ for the room temperature polymerization of D,L-lactide affording highly heterotactic polylactide of controlled molecular weight and narrow molecular weight distribution.

In the title compound, [Pd(C11H13ClN)Cl(C8H7N)], which crystallized in the chiral space group P212121, the Pd(II) atom is coordinated by two C atoms, a Csp(2) atom of the 2-chloro-3-dimethyl-amino-1-phenyl-prop-1-en-1-yl ligand and a Csp atom from the benzyl isocyanide ligand, as well as an N atom of the ligand and a Cl atom, in a square-planar geometry. In the complex, there is a short C-H⋯Cl ...

The composition of a dynamic mixture of similar 2,2'-bipyridine complexes of iron(II) bearing either an amide (5-benzylamido-2,2'-bipyridine and 5-(2-methoxyethane)amido-2,2'-bipyridine) or an ester (2,2'-bipyridine-5-carboxylic acid benzylester and 2,2'-bipyridine-5-carboxylic acid 2-methoxyethane ester) side chain have been evaluated by electrospray mass spectroscopy in acetonitrile. The time...

Effects of N-dodecyl-N,N-dimethyl-N-benzylammonium halides (DBeAX) on thermotropic phase behavior of phosphatidylcholine/cholesterol bilayers as well as on 1H NMR spectra were studied. The surfactants were added either to the water phase or directly to the lipid phase (a mixed film was formed). The benzyl group, opposite to liposomes without cholesterol, is not incorporated into the bilayer in ...

The production of lung adenomas in strain A mice following multiple injections of 17 alkyl halides and of 3 base analogs was investigated. A slight but significant increase in the average number of lung tumors per mouse was noted following the administration of methyl iodide, n and i-propyl iodide, secand tert-butyl chloride, i-, sec-, and tert-butyl bromide, and nand sec-butyl iodide. The admi...