The photochemistry of the pyrazolo[1,2-a]benzotriazole 1b and its dimethyl derivative 1c was studied in argon matrices at 12 K and in solution at 190 K. On irradiation at 365 nm, 1b and 1e undergo ring closure to yield the triazasemibullvalenes 2b and 2c, respectively, which were identified unambiguously by NMR and IR spectroscopy. This novel type of cyclization is reversed on warming or by irr...

Abstract A convenient synthetic method for the preparation of novel NSAID twin esters 6a-i containing amino acid residue, urea and amide moieties has been developed. The synthetic pathway applied for the preparation of target compounds and key intermediates 1-benzotriazolecarboxylic acid chloride (1), NSAID benzotriazolides 2a-c and N-(1-benzotriazolecarbonyl)-amino acids 3a-d involved benzotri...

Flexible and asymmetric ligand L [L = 1-((pyridin-3-yl)methyl)-1H-benzotriazole], is used as a basic backbone to construct complicated metal-organic frameworks. Two new polymers, namely, [Ag(2)(L)(2)(NO(3))(2)](n) (1) and [Ag(L)(ClO(4))](n) (2), were synthesized and characterized by X-ray structure analysis and fluorescent spectroscopy. The complex 1 gives an "S" type double helical conformatio...

Eighteen (2RS,6RS)-2-(4-methoxyphenyl)-6-(substituted ethyl)dihydro-2H-pyran-4(3H)ones were synthesized via a DDQ-mediated oxidative carbon-hydrogen bond activation reaction. Fourteen of these tetrahydropyrans were substituted with triazoles readily assembled via azide-alkyne click-chemistry reactions. Examples of a linked benzotriazole and pyrazole motif were also prepared. To complement the s...

In the title complex, [Cd(C(6)H(4)N(3)O(3)S)(2)(C(10)H(8)N(2))], the Cd(2+) cation is located on a twofold rotation axis and is coordinated by two N and two O atoms from two symmetry-related benzotriazole-4-sulfonate anions and two N atoms from a 2,2-bipyridyl ligand, displaying a distorted CdN(4)O(2) octa-hedral geometry. The crystal structure is stabilized by N-H⋯O and C-H⋯O hydrogen-bonding ...

In the title complex, [Pd(C(20)H(15)N(4)O)(2)], the Pd(II) atom is tetra-coordinated by two N atoms and two O atoms from two bidentate imine-benzotriazole phenolate ligands, forming a square-planar environment. The asymmetric unit contains two half-mol-ecules in both of which the Pd(II) atom lies on a centre of symmetry. The average distances between the Pd(II) atom and the coordinated O and N ...

In view of the biological and clinical importance of Benzotriazole compounds, some new derivatives were synthesized and characterized on the basis of analytical and spectral data. All the new compounds were evaluated at 500μg/ml, 250μg/ml and 100μg/ml for the antibacterial and antifungal activity. Some of the compounds showed moderate to good antimicrobial activity against gram positive and gra...