نتایج جستجو برای: benign cortical epilepsy
تعداد نتایج: 229833 فیلتر نتایج به سال:
Absence seizures are the most pure form of generalized epilepsy. They are characterized in the electroencephalogram by widespread bilaterally synchronous spike-wave discharges (SWDs), which are the reflections of highly synchronized oscillations in thalamocortical networks. To reveal network mechanisms responsible for the initiation and generalization of the discharges, we studied the interrela...
Background: Patients with LAMA2-congenital muscular dystrophy (CMD) usually present a severe phenotype characterized by inability to achieve walking capacity, multiple joint deformities, and respiratory insufficiency. However, there is gravity spectrum, some patients can walk unassisted. Characteristically, the have white matter changes in T2-WI FLAIR brain magnetic resonance. More rarely, cort...
Neurostimulation is a promising treatment for refractory epilepsy. We studied the effect of cortical stimulation with different parameters in the rat motor cortex stimulation model. High intensity simulation (threshold for motor response--100 μA), high frequency (130 Hz) stimulation during 1 h decreased cortical excitability, irrespective of the interpulse interval used (fixed or Poisson distri...
Acute cerebral cortical trauma often leads to paroxysmal activities that terminate in a few hours, but several months later, patients can develop epilepsy. The process occurring between the initial acute triggered seizures and the onset of spontaneous unprovoked seizures is termed epileptogenesis. Here the authors summarize recent morphological, electrophysiological, and computational studies d...
Approximately 30 percent of epilepsy patients suffer from refractory temporal lobe epilepsy which is commonly treated with resection of the epileptogenic tissue. However, surgical treatment presents many challenges in locating the epileptogenic focus and thus not all patients become seizure-free following surgery. Advances in techniques can lead to improved localization of the epileptogenic zon...
Brief-pulse stimulation at 50 Hz has been shown to terminate afterdischarges observed in epilepsy patients. However, the optimal pulse stimulation parameters for terminating cortical electrical stimulation-induced afterdischarges remain unclear. In the present study, we examined the effects of different brief-pulse stimulation frequencies (5, 50 and 100 Hz) on cortical electrical stimulation-in...
The role of transcranial magnetic stimulation in epileptology is discussed in this article. Usefulness of TMS are discussed as a diagnostic tool in testing altered cortical excitability in patients with epilepsy and the modes of action of antiepileptic drugs, which are helpful to evaluate the pathophysiology of epilepsy. Also potential therapeutic tool in epilepsy with repetitive transcranial m...
Progressive functional decline in the epilepsies is largely unexplained. We formed the ENIGMA-Epilepsy consortium to understand factors that influence brain measures in epilepsy, pooling data from 24 research centres in 14 countries across Europe, North and South America, Asia, and Australia. Structural brain measures were extracted from MRI brain scans across 2149 individuals with epilepsy, di...
Investigators from University of Gaziantep, Turkey described the clinical and EEG findings of patients with benign epilepsy of childhood with centrotemporal spikes (BECTS) experiencing postictal Todd paralysis.
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