نتایج جستجو برای: basophil
تعداد نتایج: 2051 فیلتر نتایج به سال:
Basophilic granulocytes (usually referred to as basophils) are a small population of peripheral blood leukocytes containing cytoplasmatic granules that stain with basophilic dyes. They were first described in 1879 by Paul Ehrlich,1 who 1 year earlier had found a morphologically similar cell type present in tissues that he termed Mastzellen.2 Based on their similarity to mast cells, basophils ha...
Optimizing of the basophil activation test: Comparison of different basophil identification markers.
BACKGROUND Flowcytometric identification of basophils is a prerequisite for measuring activation of basophils with IgE-dependent or IgE-independent stimuli. Aim of this study was to compare different marker combinations in a simultaneous multicolor flowcytometric measurement. METHODS Ten patients with a grass pollen allergy and three controls were included in the study. Basophilic cells were ...
BACKGROUND Basophils are an active participant in the pathogenesis of local inflammation in allergic diseases such as asthma, but it is not fully known how basophil activation is regulated in inflamed tissue. OBJECTIVE In order to clarify the control mechanisms of basophil activation in chronic inflammation and at remodeling sites, we analyzed the effects of fibroblast-derived cytokines, stem...
A LTHOUGH MAMMALIAN BASOPHILS and mast cells may share a common hematopoietic precursor,’ these cells express different functions and biochemical properties.2’3 In many species, basophils participate prominently in delayed hypersensitivity to biologically important antigens such as contact allergens, soluble proteins, parasites, allografts, viruses, and tumors.2’3 The mouse had long been consid...
INTRODUCTION Pathological changes of severe chronic allergic conjunctivitis are driven not only via acquired immunity but also via innate immunity. Type 2 immune response-initiating cytokines may play some roles as innate immunity-dependent components of the ocular surface inflammation. To investigate the involvement of type 2 immune response-initiating cytokines in innate immunity-dependent, p...
Although fluoroquinolones (FQs) are generally well-tolerated antibiotics, increasing numbers of hypersensitivity reactions have been reported. These can be evaluated in vitro by basophil activation tests (BATs); however, sensitivity is not optimal. Many factors could influence sensitivity such as basophil activation markers. The objective of this study was to evaluate the influence of 2 differe...
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