نتایج جستجو برای: basement membrane
تعداد نتایج: 392646 فیلتر نتایج به سال:
PURPOSE To determine whether the native basement membrane left behind after manual débridement wounding is retained throughout healing in the Balb/c mouse. METHODS Mouse corneas were subjected to either 1.5 mm (small) or limbus-to-limbus (large) epithelial débridement wounds and allowed to heal for times ranging from 12 hours to 3 days. For the larger wounds, care was taken to leave an approx...
The basement membrane (BM) is a special type of extracellular matrix and presents the major barrier cancer cells have to overcome multiple times form metastases. Here we show that BM stiffness determinant metastases formation in several tissues identify netrin-4 (Net4) as key regulator stiffness. Mechanistically, our biophysical functional analyses combination with mathematical simulations Net4...
The basement membrane, a thin extracellular matrix, plays a critical role in tissue development and repair. Laminins are the major component of basement membrane and have diverse biological activities. We have identified various cell-adhesive peptides from laminins and their specific cell surface receptors. Polysaccharides, including chitosan, have been used as scaffolds, which regulate cellula...
Megakaryocytes give rise to platelets via extension of proplatelet arms, which are released through the vascular sinusoids into the bloodstream. Megakaryocytes and their precursors undergo varying interactions with the extracellular environment in the bone marrow during their maturation and positioning in the vascular niche. We demonstrate that podosomes are abundant in primary murine megakaryo...
Elastase is an elastin lytic enzyme that inhibits the deposition of fat on arterial walls and suppresses fat buildup. The changes in the renal glomerular basement membrane were observed over 30days ofelastase administration in N. Y. S. mice (experimental congenital diabetic animals). and the treated group showed a lessening in the thickening of the basement membrane. The thichness of the baseme...
Graded dextrans were used as tracers to study glomerular permeability in nephrotic rats. Two narrow range fractions were used, one which was approximately the same size as albumin (62,000 mol wt) and one which was considerably larger (125,000 mol wt). Nephrosis was induced with daily injections of an aminonucleoside of puromycin, and the animals examined after 7 days, when proteinuria is minima...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید