The molecular diversity of Epstein–Barr virus (EBV) is exceptionally complex and based on the characterization sequences coding for several viral genes. aim this study was to analyze distribution EBV types 1 2 characterize LMP1 variants in a cohort 73 patients with infectious mononucleosis (IM), as well investigate possible association between relevant clinical parameters. Population-based sequ...

UNLABELLED Epstein-Barr virus (EBV) is a ubiquitous gammaherpesvirus associated with both B cell and epithelial cell malignancies. EBV infection of B cells triggers activation of several signaling pathways that are critical for cell survival, virus latency, and growth transformation. To identify EBV proteins important for regulating cell signaling, we used a proteomic approach to screen viral p...

Epstein-Barr virus (EBV) immortalizes host cells as part of its latent mode of infection. As a result of this ability to promote cell proliferation and survival, EBV infection contributes to the development of several kinds of B-cell lymphomas and epithelial tumours. The EBV Epstein-Barr nuclear antigen 1 (EBNA1) protein is the only EBV protein expressed in all EBV-associated tumours and plays ...

EBV: Epstein-Barr virus ENKTCL: natural killer/T-cell lymphoma, nasal type NHL: non-Hodgkin’s lymphoma NK: natural killer PEG: polyethylene glycol TIA-1: T-cell intracellular antigen

background: our aim was to detect the rate of toxoplasma gondii infections and the coinfections in childbearing age women in turkey accompanying using seroprevalence data from a multicenter hospital setting. methods: overal, 17751 childbearing age women through 16-45 years were included to the study between 2004 and 2010. the clinical samples of the patients were collected from 16 hospitals and...

Pinus massoniana bark extract (PMBE) at a concentration of 60 microg/mL or more inhibits the expression of Epstein-Barr virus (EBV) lytic proteins, such as Rta, Zta, and EA-D. EBV lytic cycle was blocked by inhibiting the transcription of immediate-early genes. The results suggest that the PMBE has anti-EBV activity. Thus, the extract is potentially useful in preventing the lytic development of...

Recent evidence has shown that Hodgkin‘s disease (HD) is associated with Epstein-Barr virus (EBV) in a substantial number of cases and that in these cases EBV DNA is localized exclusively to Hodgkin and Reed-Sternberg (RS) cells. The virus genome is not silent in RS cells because two EBV latent gene products, latent membrane protein (LMP) and EB early region (EBER) transcripts, have recently be...

Southern China experiences larger extent of total cancer pathologies, of which nasopharyngeal carcinoma has the highest incidence under otorhinolaryngeal malignant carcinomas. Risk factor of nasopharyngeal carcinoma varies from hereditary causes to virus infection, among which Epstein-Barr virus (EBV) infection is the mostly investigated. The study into mechanism of EBV in occurrence, developme...

Abstract The objective of this study was to detect the Epstein–Barr virus (EBV) coinfection in coronavirus disease 2019 (COVID-19). In retrospective single-center study, we included 67 COVID-19 patients with onset time within 2 weeks Renmin Hospital Wuhan University from January 9 February 29, 2020. Patients were divided into EBV/SARS-CoV-2 group and SARS-CoV-2 infection alone according serolog...

Chronic active Epstein-Barr virus infection (CAEBV) has been considered to be a non-neoplastic T-cell lymphoproliferative disease associated with Epstein-Barr virus (EBV) infection. In EBV-associated diseases, the cell phenotype-dependent differences in EBV latent gene expression may reflect the strategy of the virus in relation to latent infection. We previously reported that EBV latent gene e...