OBJECTIVES To review relevant literature and present evidence-based guidelines to assist general and specialist medical practitioners in the evaluation and management of children who present with chronic cough. METHODOLOGY The Cochrane, MEDLINE, and EMBASE databases, review articles, and reference lists of relevant articles were searched and reviewed by a single author. The date of the last c...

The objective of the present study was to evaluate the prevalence of chronic cough causes and to compare the efficacy of two diagnostic approaches used in ambulatory vs. hospitalized setting. Eighty patients with chronic cough, 40 in each group, were enrolled into the study. The etiology of cough was determined on medical history and on either basic (in out-patients) or detailed (in in-patients...

Changes in the characteristics of the cough sound may refer to some specific pathological processes and their evolution. In this pilot study we analyzed voluntary cough sound properties in subjects with asthma bronchiale (AB) and chronic obstructive pulmonary disease (COPD) and discriminated them from the control cough sound in healthy subjects. The wavelet transform was used due to a nonstatio...

RATIONALE Chronic persistent cough can be associated with laryngeal dysfunction that leads to symptoms such as dysphonia, sensory hyperresponsiveness to capsaicin, and motor dysfunction with paradoxical vocal fold movement and variable extrathoracic airflow obstruction (reduced inspiratory airflow). Successful therapy of chronic persistent cough improves symptoms and sensory hyperresponsiveness...

Introduction Each year 7 million people die of stroke worldwide; most deaths are caused by chest infections. Patients with acute stroke have impaired voluntary cough flow, associated with increased risk of chest infections. Reduced functional residual capacity (FRC) could lead to impaired cough flow. We therefore compared FRC in acute hemiparetic stroke patients and controls and explored its re...

background: re-emergence of pertussis has been reported in iran despite a high rate of vaccination coverage. low efficacy of the vaccine might be due to the genetic divergence between clinical versus vaccine strains. in the current study, the genetic profiles of clinical isolates and vaccine strains of bordetella pertussis (b. pertussis) were assessed by using pulsed field gel electrophoresis (...

Cough, one of the most common reasons patients seek medical attention [1], is categorised according to duration. Acute cough lasts ,3 weeks, subacute cough lasts 3–8 weeks and chronic cough .8 weeks [2, 3]. Acute cough is usually due to viral infection; it is transient and self-limiting [4]. Chronic cough has a variety of causes that can be established in 88–100% of patients using a diagnostic ...

Cough is a primitive reflex typically consisting of an initiating deep inspiration, glottal closure, and an explosive expiration accompanied by a sound. The flow characteristics of cough have been shown to differ between different pulmonary diseases. Cough sounds are generated at the larynx and in the lungs. Modern analysing techniques have also been applied in cough sound studies, and differen...

Statement of Interest: Statements of interest for S. Birring and I. Pavord can be found at www.erj.ersjournals.com/site/misc/ statements.xhtml REFERENCES 1 Pavord ID, Chung KF. Management of chronic cough. Lancet 2008; 371: 1375–1384. 2 Morice AH, McGarvey L, Pavord ID. Recommendations for the management of cough in adults. Thorax 2006; 61: 1–24. 3 Birring SS, Fleming T, Matos S, et al. The Lei...

CONTENTS Summary of key points and recommendations . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1256 Background . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1257 Capsaicin and citric acid inhalation cough challenge . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1258 Cough induced by ...