نتایج جستجو برای: balbc mice embryos
تعداد نتایج: 432198 فیلتر نتایج به سال:
Background: Vitrification has been usually used as an assisted reproductive technology in animals and humans. This method needs high concentrations of cryoprotectants that can be toxic with high cooling degrees. Then, vitrification could be change histone modifications such as methylation and acetylation can performance as regulatory controls of gene transcription. So, the purpose of the presen...
BACKGROUND Chronic obstructive pulmonary disease presents with two different phenotypes: chronic bronchitis and emphysema with parenchymal destruction. Decreased expression of vascular endothelial growth factor and increased endothelial cell apoptosis are considered major factors for emphysema. Stem cells have the ability of vascular regeneration and function as a repair mechanism for the damag...
Heparin-binding EGF-like growth factor (HB-EGF) is a member of the EGF family of growth factors that binds to and activates the EGF receptor (EGFR) and ERBB4. Here, we show that HB-EGF-EGFR signaling is involved in eyelid development. HB-EGF expression is restricted to the tip of the leading edge of the migrating epithelium during eyelid closure in late gestation mouse embryos. Both HB-EGF null...
BACKGROUND Vascular patterning depends on coordinated timing of arteriovenous specification of endothelial cells and the concomitant hemodynamic forces supplied by the onset of cardiac function. Using a combination of 3D imaging by OPT and embryo registration techniques, we sought to identify structural differences between three different mouse models of cardiovascular perturbation. RESULTS E...
Purpose: To determine the effects of different doses of addition of exogenous epidermal growth factor (EGF) on development of pre-implantation mouse embryo. Materials and Methods: Mouse zygotes, two cell, 8 cell any morulae were collected from superovulated NMRI mice 24, 48, 64 and 80 hrs after hCG injection, respectively. The obtained embryos were cultured on medium alone, medium with 1, 4 an...
Background and purpose: Oxidative stress induced by cyclophosphamide (CP), a chemotherapeutic agent, causes vulnerability of sperm and declining the fertility power. Then in this study the effect of crocin (saffron extract) on amelioration of these side effects was investigated. Materials and methods: In this study 24 adult male mice were divided in three groups (n=8). Control group received n...
Background: Decreasing the growth and developmental rate of embryo and arresting in certain step of development like two cell block could be the reason of infertility in some couples referring to fertility and infertility center. The aim of this study is the effect of strontium on growth and development of two-cell arrested NMRI mouse embryo. Materials and Methods: The female mice were coupled ...
Leflunomide is an antirheumatic drug commonly used by females, as this disease common in females and there are chances of pregnancy while taking medication initial months prescribed lacks studies related to its teratogenic potential. Present study was conducted know about teratogenicity mice embryos. Pregnant were exposed oral route on gestational days 6 11 either single dose one the or continu...
Background The aim of this study is to examine the effects of cranberry extract prescription in sensitive days of pregnancy on development and histomorphometric changes in liver of mouse embryo. MaterialsAndMethods A total of 24 pregnant mice were divided into equal 4 groups. The control group received no injection, while sham group was injected with saline and experimental groups were given cr...
Background & Aims: Cyclophosphamide (CP) has been known as an immunosuppressant agent, and is reported to induce oxidative stress. It also impacts gonadal cells nucleus and reduce the fertilizing potential. Therefore, the present study was aimed to evaluate the protective effects of Ethyl Pyruvate as a potential antioxidant on in vitro fertilized embryos development following exposure to CP. ...
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