نتایج جستجو برای: bacterial cystitis

تعداد نتایج: 208590  

Journal: :The Journal of clinical investigation 1997
K Thankavel B Madison T Ikeda R Malaviya A H Shah P M Arumugam S N Abraham

The FimH subunit of type 1-fimbriated Escherichia coli has been implicated as an important determinant of bacterial adherence and colonization of the urinary tract. Here, we sought to localize the functionally important domain(s) within the FimH molecule and to determine if antibodies against this domain would block adherence of type 1-fimbriated E. coli to the bladder mucosa in situ and in viv...

Journal: :Journal of immunology 2012
Benjamin L Duell Alison J Carey Chee K Tan Xiangqin Cui Richard I Webb Makrina Totsika Mark A Schembri Petra Derrington Helen Irving-Rodgers Andrew J Brooks Allan W Cripps Michael Crowley Glen C Ulett

Early transcriptional activation events that occur in bladder immediately following bacterial urinary tract infection (UTI) are not well defined. In this study, we describe the whole bladder transcriptome of uropathogenic Escherichia coli (UPEC) cystitis in mice using genome-wide expression profiling to define the transcriptome of innate immune activation stemming from UPEC colonization of the ...

Journal: :Infection and immunity 2011
Drew J Schwartz Swaine L Chen Scott J Hultgren Patrick C Seed

Urinary tract infections (UTIs) have complex dynamics, with uropathogenic Escherichia coli (UPEC), the major causative agent, capable of colonization from the urethra to the kidneys in both extracellular and intracellular niches while also producing chronic persistent infections and frequent recurrent disease. In mouse and human bladders, UPEC invades the superficial epithelium, and some bacter...

2012
Kimberly B Ulett Jennifer H Shuemaker William H Benjamin Chee K Tan Glen C Ulett

INTRODUCTION Streptococcus agalactiae or group B streptococcus is a Gram-positive pathogen that is typically associated with neonatal disease and infection in pregnant women. Group B streptococcus also causes invasive infections in non-pregnant adults including urinary tract infections. The spectrum of urinary tract infections caused by group B streptococcus includes cystitis, pyelonephritis, u...

Journal: :The Journal of Experimental Medicine 1995
J Winberg R Möllby J Bergström K A Karlsson I Leonardsson M A Milh S Teneberg D Haslam B I Marklund S Normark

Human urinary tract infection is an infectious disease that depends on a series of host-microbial interactions. The bacteria first colonize the colon and then the periurethral/vaginal areas; they ascend to and infect first the bladder and then the kidneys. Expression of Escherichia coli P-fimbriae constitutes the strongest correlation to renal pathogenicity, but is also related to first-time cy...

Journal: :Journal of Emergency Medicine Case Reports 2019

Journal: :The Journal of urology 2014
Lisa A Kilpatrick Jason J Kutch Kirsten Tillisch Bruce D Naliboff Jennifer S Labus Zhiguo Jiang Melissa A Farmer A Vania Apkarian Sean Mackey Katherine T Martucci Daniel J Clauw Richard E Harris Georg Deutsch Timothy J Ness Claire C Yang Kenneth Maravilla Chris Mullins Emeran A Mayer

PURPOSE The pathophysiology of interstitial cystitis/painful bladder syndrome remains incompletely understood but is thought to involve central disturbance in the processing of pain and viscerosensory signals. We identified differences in brain activity and connectivity between female patients with interstitial cystitis/painful bladder syndrome and healthy controls to advance clinical phenotypi...

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