Nucleophosmin (B23) was phosphorylated in vitro with [gamma-32P]ATP and a nuclear kinase (type II) purified from HeLa cells. The phosphorylation was inhibited by heparin and by 2,3-diphosphoglycerate. Peptide mapping analysis indicated that the phosphorylation site in vitro was identical to that in vivo. Purified nucleoli have a similar kinase that phosphorylated nucleophosmin at the same site....

Rękopis z II połowy XV wieku proweniencji Katedry Krakowskiej, dziś w zbiorach Biblioteki oo. Paulinów na Skałce Krakowie, sygnatura B23 (=BSkałka/Kraków B23) zawiera dwie kolekcje Sermones de sanctis anonimowych autorów. W jednym trzech zachowanych tam kazań De divisione Apostolorum, anonimowy kaznodzieja, pamiątkę zwycięstwa 15 lipca 1410 roku sprzymierzonych wojsk polskich króla Władysława J...

The evolutionary mechanisms responsible for the loss of eyes in cave animals are still unresolved. Hypotheses invoking natural selection or neutral mutation have been advanced to explain eye regression. Here we describe comparative molecular and developmental studies in the teleost Astyanax mexicanus that shed new light on this problem. A. mexicanus is a single species consisting of a sighted s...

A group of 61 unselected patients with psoriasis attending a dermatology clinic were studied to determine the prevalence of psoriatic arthritis. On defined criteria arthritis was present in 41.6%. Peripheral arthritis was present in 15.5%, and sacroiliitis in 43%. A strong association of distal interphalangeal arthritis with psoriasis and nail dystrophy was confirmed. Tissue typing showed a str...

Solar Water Disinfection (SODIS) is a simple process used in developing countries to improve the quality of bacteria-contaminated drinking water. A previous study found that phthalate, an aromatic compound released by polyethylene terephthalate (PET) bottles upon UV-A irradiation, enhanced the germicidal activity of SODIS. In the current study, two possible mechanisms behind this observation we...