نتایج جستجو برای: axon regeneration

تعداد نتایج: 79002  

2004
Yinghua Zhu Julius Zhu Barbara Grimpe Mitchell F. Roitman Garret D. Stuber Paul E. M. Phillips R. Mark Wightman Regina M. Carelli

Specific sensory input to neocortex arrives in layer 4, whereas nonspecific input, such as information about salience or novelty, is thought to arrive in layer 1. This scheme might imply a slower arrival of inputs to layer 1. In this issue, Zhu and Zhu examine this question using paired whole-cell recording in vivo from layer 1 nonpyramidal cells and the dendrites of the output pyramidal neuron...

Journal: :Neuron 2012
Paola Nix Michael Bastiani

In this issue of Neuron, Shin et al. (2012) show that the dual leucine zipper kinase (DLK) is responsible for the retrograde injury signal in spinal sensory and motor neurons. DLK is required for the accelerated regeneration seen after axotomy and for the improved regeneration seen after a conditioning injury. DLK KO axons have severely reduced axon regeneration in vivo.

Journal: :Neural Regeneration Research 2015

Journal: :Current Biology 2012
Shiri P. Yaniv Noa Issman-Zecharya Meital Oren-Suissa Benjamin Podbilewicz Oren Schuldiner

BACKGROUND The molecular mechanisms that determine axonal growth potential are poorly understood. Intrinsic growth potential decreases with age, and thus one strategy to identify molecular pathways controlling intrinsic growth potential is by studying developing young neurons. The programmed and stereotypic remodeling of Drosophila mushroom body (MB) neurons during metamorphosis offers a unique...

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