Gross and microscopic lesions of pasteurellosis were studied in control and immunized pasteurella-free rabbits after challenge with virulent Pasteurella multocida. Pathologic responses were compared in rabbits immunized intravenously or mucosally with P. multocida or with J5, a cross protective core LPS mutant of E. coli. All rabbits were challenged conjunctivally with approximately 2xLD50 of P...

Pasteurella multocida is among the most important respiratory pathogens of cattle. Outer-membrane protein (OmpH) constitutes an essential bacterial antigen and is well studied in avian bacterial strains. Studies on isolates from cattle with signs of respiratory disease caused by Pasteurella multocida serotypes A and D have not yet been covered in the literature. The objective of this study was ...

Lesions of calf pneumonia caused by Pasteurella haemolytica or P. mu/t,ocida were examined histopathologically using an immunoperoxidase technique for the detection of the bacterial antigen. The results indicated that: 1) multifocal coagulation necrosis sharply demarcated by degenerated leukocytes was a characteristic pulmonary lesion caused by P. haemolytica, 2) other bacteria than P. haemolyt...

Pasteurella multocida produces a 146-kDa protein toxin (Pasteurella multocida toxin, PMT), which stimulates diverse cellular signal transduction pathways by activating heterotrimeric G proteins. PMT deamidates a conserved glutamine residue of the α-subunit of heterotrimeric G proteins that is essential for GTP-hydrolysis, thereby arresting the G protein in the active state. The toxin substrates...

pasteurella multocida is considered to be an important cause of ovine pneumonia and results causes considerable economic losses in iran. ribotyping pcr (ribo-pcr) was used for investigating the diversity of ovine and caprine p.multocida. a total of 120 swab tonsil and nasal samples were obtained from sheep and goats. they were analyzed by biochemical tests and ribo-pcr 16s-23s ribosomal rna gen...

We studied the comparative in vitro activities of 10 oral antimicrobial agents against 147 aerobic and 61 anaerobic bacteria making up species in 13 genera (Staphylococcus aureus, streptococci, Eikenella corrodens, Pasteurella multocida, Haemophilus-Actinobacillus spp., M-5, EF-4, Moraxella spp., Flavobacterium IIb, Bacteroides melaninogenicus, Bacteroides spp., Fusobacterium spp., and Peptostr...

Pasteurella multocida appears to be a very rare cause of meningitis. The bacterium has morphological similarities with other causative organisms, particularly Haemophilus influenzae, and its apparent rarity may be due partly to misidentification. This case, only the fourth reported from the United Kingdom, could not be distinuished clinically from the meningitis, owing to other pyogenic bacteria.

Haemorrhagic septicemia (HS) caused by Pasteurella multocida (serotype B: 2) is an important disease of cattle and buffaloes in Asian sub-continent. Presently available vaccines for HS have their own limitations. Efforts have been made to develop better vaccine targeting outer membrane proteins and few of them have shown potential . Omp 87 protein has shown a protective potential against fowl c...