The following review is based on notes used in the teaching of clinical immunology to veterinary students. Immune diseases of the dog are placed into six different categories: (1) type I or allergic conditions; (2) type II or auto- and allo-antibody diseases; (3) type III or immune complex disorders; (4) type IV or cell-mediated immune diseases; (5) type V conditions or gammopathies; and (6) ty...

A 31-year-old woman with primary mediastinal large B-cell lymphoma refractory to conventional chemotherapy was treated with high-dose chemotherapy containing cyclophosphamide (CY). Subsequently, she was treated with auto peripheral blood stem cell transplantation. Although a complete remission was obtained, heart failure developed two months later. Echocardiography showed an impaired systolic f...

BACKGROUND AND OBJECTIVES Laparoscopic surgery has rapidly expanded in surgical practice with well-accepted benefits of minimal incision, less analgesia, better cosmetics, and quick recovery. The surgical technique for kidney transplantation has remained unchanged since the first successful kidney transplant in the 1950s. Over the past decade, there were only a few case reports of kidney transp...

Multiple myeloma (MM) remains incurable despite widespread deployment of novel agents and high-dose melphalan/autologous stem cell transplantation (ASCT) earlier in the disease course. Recently, non-myeloablative (NMA) allogeneic stem cell transplantation (allo SCT) has been introduced in an attempt to exploit the well-documented graft-versus-myeloma effect (GVM), while at the same time reducin...

Searching The searches were conducted by two independent reviewers in two different medical literature systems (MEDLINE and TOXLINE) from January 1979 to August 1996. The following keywords were used in different combinations: 'cyclosporine', 'adverse effects', 'nephrotoxicity', 'auto-immune diseases', 'uveitis', 'psoriasis', 'rheumatoid arthritis' and 'inflammatory bowel disease'. Additional p...

unctional abnormalities of cardiac troponin caused by either mutations or auto-antibodies can induce dilated cardiomyopathy (DCM),1,2 which is characterized by left ventricular enlargement and systolic dysfunction resulting from a reduction in the myocardial force of contraction. DCM causes congestive heart failure, which can be treated with diuretics, angiotensin-converting enzyme inhibitors (...

Cancer treatment modalities are increasingly more effective in achieving complete remission and cure. Aggressive chemotherapy and radiotherapy, as well as bone marrow transplantation, results in >90% cure in many cancers of children and young women. As a result of this success however, a new problem has arisen. Many young women survive to live the rest of their lives in menopause, and have no c...

The treatment of animals with non-neoplastic or neoplastic tissue before or after tumor transplantation inhibited the growth of transplanted tumor cells. This phenomenon was most clearly demonstrated when a sub-effective dose of chemotherapeutic agent was administered. In animals bearing a spontaneous tumor, the growth of auto-transplanted tumor was inhibited as compared with that of the same t...

Splenosis is auto transplantation of splenic tissue following traumatic rupture of the spleen. In females it can mimic endometriosis when symptomatic. Asymptomatic splenosis is common than previously suspected and it can also involve ovary. In a patient with a history of splenectomy, splenosis can act and provide the function of the spleen and thus should not be routinely excised. We report a c...

Lymphoblastic lymphoma (LBL) is a rare, clinically aggressive neoplasm of the young that frequently involves the bone marrow (BM) and/or central nervous system. Because LBL is similar to acute lymphoblastic leukemia, some centers prefer allogeneic hematopoietic stem cell (SC) transplantation to autologous SC transplantation. We retrospectively analyzed outcomes for patients who underwent autolo...