نتایج جستجو برای: atovaquone

تعداد نتایج: 456  

2017
Holly Matthews Jon Deakin May Rajab Maryam Idris-Usman Niroshini J Nirmalan

The widespread introduction of artemisinin-based combination therapy has contributed to recent reductions in malaria mortality. Combination therapies have a range of advantages, including synergism, toxicity reduction, and delaying the onset of resistance acquisition. Unfortunately, antimalarial combination therapy is limited by the depleting repertoire of effective drugs with distinct target p...

2012
Miriam K. Laufer Phillip C. Thesing Fraction K. Dzinjalamala Osward M. Nyirenda Rhoda Masonga Matthew B. Laurens Abbie Stokes-Riner Terrie E. Taylor Christopher V. Plowe

BACKGROUND The predominance of chloroquine-susceptible falciparum malaria in Malawi more than a decade after chloroquine's withdrawal permits contemplation of re-introducing chloroquine for targeted uses. We aimed to compare the ability of different partner drugs to preserve chloroquine efficacy and prevent the re-emergence of resistance. METHODOLOGY/PRINCIPAL FINDINGS Children with uncomplic...

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