b) at this chromosome 11q location and atopy by maternal descent. The identification of this Background – FceRI plays a central role in atopy, thus genetic variants of FceRI-b variant DNA has proved problematic, perhaps because of protein/DNA binding at the site, may alter receptor function to enhance atopic responses and may manifest as a but the variants we report have been confirmed by direc...

Atopic eczema/dermatitis syndrome is a term that covers different subtypes of atopic dermatitis. The "intrinsic" type of atopic dermatitis is non-IgE-associated, and the "extrinsic" type is IgE-associated atopic eczema/dermatitis syndrome. In the etiopathogenesis of atopic dermatitis there are well known interactions among genetic, environmental, skin barrier, immune factors, and stress. Geneti...

PURPOSE Viral infection is the most common aggravating factor for childhood asthma. Asthma may be a risk factor for severe respiratory symptoms in children with lower respiratory tract infections of viral etiology. Influenza A infection enhances Th2-polarization to house dust mites during the acute phase and leads to lung dysfunction in a mouse model. However, there are no data on the relations...

Atopic dermatitis skin tends to be easily irritated and appears dry. These clinical peculiarities correspond to impaired barrier function and to increased transepidermal water loss (TEWL) values. A few studies suggest that a reduced amount of total ceramides (especially of ceramide 1) is responsible for functional abnormalities of the skin of atopic dermatitis patients. The aim of this study wa...

Methods: We divided 360 atopic dermatitis patients into six groups in the treatment frequency to compare a treatment effect. We investigated the existence of the diurnal secretion quantity change of adrenal cortex hormone to judge the present condition of the adrenal cortex functions of 1,699 atopic dermatitis patients and bronchial asthma patients. We investigated the spinal condition of 1,028...

Adhesion molecules may play an important role in the homing of T-cell subsets into allergen-exposed skin of atopic individuals. The aim of this study was to examine the expression of adhesion molecules in atopic dermatitis skin lesions. Biopsies were obtained from lesions in 30 adult patients with atopic dermatitis and 10 healthy adults as controls. Biopsy specimens were studied by immunohistoc...

Canine Atopic Dermatitis (CAD) is the most frequent canine dermatosis. It has been defi ned by the International Task Force on Canine Atopic Dermatitis ( ITFCAD) as a “genetically predisposed infl ammatory and pruritic allergic skin disease with characteristic clinical features associated with IgE antibodies most commonly directed against environmental allergens”[1]. A ITFCAD-revised nomenclatu...

The atopic diseases - atopic dermatitis, asthma, and hay fever - pose a great burden to the individual and society, not least, since these diseases have reached epidemic proportions during the past decades in industrialized and, more recently, in developing countries. Whereas the prevalence of the atopic diseases now seems to have reached a plateau in many Western countries, they are still on t...

Six patients with the acquired immune deficiency syndrome (AIDS) had exacerbations or recurrences of previously quiescent atopic disease when they developed immunodeficiency. Four developed a different atopic illness from that suffered previously. Atopic symptoms developed within three months after the patients developed AIDS or during prodromal illness. Two of the patients were treated with re...

emotional factors and a recurrent psychosomatic environment, have been implicated in the evolution of atopic dermatitis. these, in turn, affect the disease. this study was under taken to evaluate the functioning of families with a child that has atopic dermatitis without skin symptoms and the parents’ perceptions of their child’s disease. semi-quantitative and cross-sectional study in which que...