Cardiovascular mortality has been found to be increased in rheumatic diseases, which is attributed to accelerated atherosclerosis. 1-3 Chronic systemic inflammation is implicated as the driving force behind accelerated atherosclerosis in rheumatic diseases. 4-5 In RA, mortality due to coronary artery disease was found to be higher than general population indicating increased risk of atheroscler...

introduction: psoriasis is a chronic inflammatory skin disease characterized by plaques covered with silvery scales. psoriasis is highly prevalent in different countries in the world, including iran. several studies have reported a significant association between psoriasis and cardiovascular diseases. this study aimed to evaluate the relationship between psoriasis and cardiac disease using echo...

Accelerated cardiovascular disease is a frequent complication of renal disease. Chronic kidney disease promotes hypertension and dyslipidemia, which in turn can contribute to the progression of renal failure. Furthermore, diabetic nephropathy is the leading cause of renal failure in developed countries. Together, hypertension, dyslipidemia, and diabetes are major risk factors for the developmen...

Atherosclerosis is one of the main causes cardiovascular events, namely, myocardium infarction and cerebral stroke, responsible for a great number deaths every year worldwide. This pathology caused by progressive accumulation low-density lipoproteins, cholesterol, other substances on arterial wall, narrowing its lumen. To date, many hemodynamic studies have been conducted experimentally and/or ...

Rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) are associated with increased mortality, largely as a consequence of cardiovascular disease. Increased cardiovascular morbidity and mortality in patients with RA and SLE cannot be entirely explained by traditional risk factors, suggesting that the systemic inflammation that characterizes these diseases may accelerate atheroscleros...

ardiovascular risk factors are identifiable in childhood and are predictive of adulthood risk for coronary artery disease.1 Autopsy studies of youths have established a strong association between cardiovascular risk factors and early stages of coronary atherosclerosis.2 Longitudinal observation studies have shown that coronary heart disease (CHD) risk factors measured in adolescence predict mar...

cytomegalovirus (cmv) infection is one of the most common infections that affects humans’ cardiovascular system. although the literature includes controversial evidence for any correlation between cmv infection and arterial atherosclerosis, the majority of studies, especially those with larger patient population and stronger data stand for such a relationship. however, the number of prospective...

Cardiovascular disease is a leading cause of death and reduced quality of life worldwide. Arterial vessels are a primary target for endothelial dysfunction and atherosclerosis, which is accompanied or even driven by increased oxidative stress. Recent research in this field identified different sources of reactive oxygen and nitrogen species contributing to the pathogenesis of endothelial dysfun...

Air pollution is a worldwide contributor to cardiovascular disease mortality and morbidity. Traffic-related air pollution is a widespread environmental exposure and is associated with multiple cardiovascular outcomes such as coronary atherosclerosis, peripheral arterial disease, and myocardial infarction. Despite the recognition of the importance of both genetic and environmental exposures to t...

Our understanding of the etiology of atherosclerosis and the mechanisms by which conventional cardiovascular risk factors cause disease is incomplete. Atherosclerosis may be regarded as a process of continuous injury and abnormal repair. The diagnosis and treatment of the disease should be targeted to the various stages of this process, from the early stages of vascular injury to the stabilizat...