multiple sclerosis (ms) is an autoimmune disease of the central nervous system associated to myelin loss and neurodegeneration. clinically patients suffer from diverse symptoms and face the risk to become wheelchair-bound. at the moment ms is incurable, thus there is an unmet need for therapeutic options.

conclusions the results of this study showed a possible association between cmv infection and ms. further experimental and epidemiological studies using case-control approaches are needed to confirm this association. results anti-cmv was positive in 65 (79.3%) and 69 (77.5%) of the ms patients and healthy subjects, respectively (p= 0.853). similarly, 23 (28%) and 2 (2.2%) patients were positive...

background: multiple sclerosis (ms), the most common demyelinating disease of the cns, is immunologically mediated in genetically susceptible individuals. receptors for the fc fragment of igg (fcγr) might induce inflammatory responses through linking the humoral and cellular immune responses by targeting immune complexes to effector cells. polymorphisms in some fcγr genes are associated with va...

Abstract Background Multiple sclerosis (MS) is the most common demyelinating disease of central nervous system. Autonomic dysfunction present in a wide range patients (15–80%) that might with abnormalities regulation cardiovascular system, sleep disturbance, urinary symptoms, sexual problems, and temperature problem. Although predominant view an autoimmune inflammatory condition, changes brain ...