Background: The excessive use of artificial sweeteners now a days just to lose weight and remain fit due other reasons without knowing its effects on liver gave me thought conduct this study see whether they are safe or not for health. Aim: To the Aspartame Sucralose size rat hepatocytes compare their choose relatively sweetener routine use. Methods: Fifty adult Wistar albino rats used in were ...

The present study aimed to formulate sucrose-replaced samples with natural or synthetic sweeteners, and benchmark the temporal sensory profile of a control sample (100% sucrose). Acesulfame-K, aspartame, erythritol, rebaudioside M, sucralose replaced sucrose at four different levels (25%, 50%, 75%, 100%) in aqueous solutions. A trained panel evaluated check-all-that-apply. sweeteners showed gre...

The excessive consumption of natural sweeteners is considered to be a major cause of increase in body mass. The authors wished to establish whether hypocaloric artificial sweeteners also promoted mass gain in laboratory rats (Harlan Wistar male rats). Ad libitum sweeteners were added to the drinking water of five groups of nine male rats each weighing circa 40g: Group 1, 15% fructose; group 2, ...

This study was carried out to evaluate the effect of administration of aspartame in two doses (40mg/kg and 80mg/kg body weight) on the submandibular salivary glands of male albino rats. Ninety adult male rats weighing (200-250g) were used in this study. Animals in each group were caged in separate cages in the animal house at the Faculty of Dentistry, Minia University. Pure aspartame (APM) powd...

We describe a case of epileptic seizures after a massive intake of diet coke. Apart from the hyponatremia due to water intoxication the convulsions can be potentiated by the high dose of caffeine and aspartame from the diet coke. To our knowledge this is the first report of seizures due to excessive diet coke intake.

Aspartame is the methylester of N-alpha-aspartyl-Lphenylalanine, a polypeptide widely employed as an artificial, intense synthetic sweetener, having none or insignificant caloric values and a sweeting power higher than that of sucrose. Its use in pharmaceutical products and in nearly 6000 food products, has been approved; among its consumers are those that replace natural foods by "light" ones ...