Palladium-catalyzed cross-coupling reactions of alpha-aryl-beta,beta-difluoroenol silyl and alpha-aryl-beta-fluoroenol silyl ethers with aryl bromides proceed smoothly with good functional compatibility.

BACKGROUND Poly(vinyl alcohol) (PVA) is a synthetic biocompatible polymer that extensively used by the medical and pharmaceutical industries due to its FDA approval for in vivo applications. Its highly hydrophilic nature makes it an ideal wound dressing material, especially form of nanofibrous mats. RESULTS In this work, electrospun PVA-based scaffolds suitable management were created. Chemical...

We disclose an unprecedented transition-metal-free carbonylative cross coupling of aryl halides with potassium aryl trifluoroborates even at atmospheric pressure of carbon monoxide. This protocol is efficient, operationally simple, and shows wide scope with regard to both aryl halides and potassium aryl trifluoroborates containing a series of active functional groups.

Deprotonation with strong bases of N-vinyl ureas carrying an N'-aryl substituent leads to migration of the N'-aryl group from N to C via an allyllithium; with weaker bases and electron-deficient aryl rings the direction of the migration reverses, and aryl substituents α to the urea N atom may migrate from C to N.

Underwood and co-workers (27) recently re ported that a number of a-ketoaldehydes and closely related compounds were active against Newcastle disease virus (NJKD strain) and in fluenza virus (PR-8 strain) in embryonated eggs. These substances also had potent virus-inactivat ing effects in vitro. Underwood and Weed (28) found that glyoxal and methylglyoxal were active virucides in blood. Consequ...