OBJECTIVE Treating tic disorder is challenging. No trial has ever examined whether twice weekly aripiprazole is effective for treating tic disorders. METHODS Participants of this 8-week randomized controlled parallel-group clinical trial were a clinical sample of 36 children and adolescents with tic disorder. Yale global tic severity scale was used to assess the outcome. Both groups received ...

BACKGROUND Aripiprazole is an atypical antipsychotic that is reported to be effective in the treatment of schizophrenia. AIMS To investigate the effects of aripiprazole on patients with schizophrenia and schizophrenia-like psychoses by conducting a systematic review of randomised controlled trials (RCTs). METHOD Database and manual searches and direct contact were used to identify relevant ...

When aripiprazole (ABILIFY) received its approval in Germany for the treatment of schizophrenia, a hospital-based postmarketing surveillance study was initiated in order to gain further insights concerning safety and efficacy of the antipsychotic under real-life conditions. Efficacy was rated by using standard CGI, GAF, and SF-12 instruments, whereas safety was evaluated according to the report...

BACKGROUND Aripiprazole can cause irreversible tardive dystonia in some individuals, and additional intervention is sometimes needed. Here, we report the first case of aripiprazole-induced irreversible tardive dystonia in which complete recovery of motor function was achieved using the antipsychotic drug clozapine. CASE PRESENTATION A 24-year-old man with bipolar disorder was treated with ari...

BACKGROUND Both the US FDA and the European Medicines Agency (EMA) have approved aripiprazole for use in adolescents for specific indications. Given the assumed favorable side-effect profile of aripiprazole, its use in children and adolescents has increased for both official and off-label indications (anxiety disorders, eating disorders, personality disorders). However, several cases of childre...

OBJECTIVE Patients with schizophrenia often experience comorbid obsessive-compulsive symptoms. Within these patients, a significant subgroup developed secondary obsessive-compulsive symptoms during treatment with clozapine. METHOD In this paper, we report on four cases in which adjunctive therapy with aripiprazole was tested to alleviate obsessive-compulsive symptoms in schizophrenia. RESUL...

PURPOSE This report describes the early onset Tardive Dyskinesia like presentation during treatment with Aripiprazole. CASE STUDY The patient, who had a history of acquired brain injury, was receiving treatment for his psychotic illness characterized by persecutory delusions, second person auditory hallucinations, self-neglect and challenging behaviours. Tardive Dyskinesia is not a well repor...

Aripiprazole, an atypical antipsychotic with a novel method of action, has only recently been awarded a license in the UK. We report our first patient to receive this drug, who had treatment-resistant schizophrenia and developed neuroleptic malignant syndrome (NMS) with aripiprazole. To our knowledge, this is the first published case report involving aripiprazole and NMS in a potentially fatal ...

s | 5 Conclusions: Aripiprazole demonstrated its efficacy in maintaining abstinence from metamphetamine use in Thai patients with metamphetamine dependence following metamphetamine psychosis. It was found to be safe and well tolerated. Keyword: methamphetamine, aripiprazole, dependence, abstinence PM294 Association between polymorphism of COMT gene and domestic violence in Han and Uygur on alco...

There are many comorbid disorders associated with autism spectrum disorders in child and adolescent population. Although obsessive compulsive disorder and autism spectrum disorders (ASD) comorbidity has common in clinical practice, there are few reports about psychopharmacological treatment for obsessive compulsive symptoms in children with ASD in the literacy. We report a successful treatment ...