Dam methylation is an essential factor involved in the virulence of an increasing number of bacterial pathogens including Salmonella enterica. Lack of Dam methylation causes severe attenuation in animal models. It has been proposed that dysregulation of Dam activity is potentially a general strategy for the generation of vaccines against bacterial pathogens. In this review, we focus our attenti...

Multiple regression of genetic evaluations for milk yields of first lactations of 159 Holstein bulls on sire, dam, and maternal grandsire evaluations indicates that the weight for estimated transmitting ability of the dam calculated from the first record of the dam and first records of her herdmates is about as theoretically expected and is markedly superior both to estimated transmitting abili...

Risk analysis methodologies can be useful tools to help decision-makers in dam safety engineering. One of the inputs needed for Quantitative Risk Analysis is an estimate of the probability of failure of the dam under study. Existing dams have been designed using the factor of safety, which is a concept associated with a certain mathematical model of the physical behavior of the dam. In dam engi...

Age-of-dam adjustment factors are used to preadjust birth and weaning weight data for national beef cattle genetic evaluations. Adjustments are used in order to make the means of the different age-of-dam subclasses similar so that a fair comparison of animals can be performed. A review was made of various research studies that have estimated age-of-dam adjustment factors for birth weight and we...

As a departure from traditional situational perspectives, researchers have given increased attention to the dispositional basis of attitudes. Recently, Hepler and Albarracín (2013) introduced a construct that they called "dispositional attitude" and provided validity evidence for a new scale--the Dispositional Attitude Measure (DAM). Although the DAM was introduced as a "new" approach for asses...

Salmonella isolates that lack or overproduce DNA adenine methylase (Dam) elicited a cross-protective immune response to different Salmonella serovars. The protection afforded by the Salmonella enterica serovar Typhimurium Dam vaccine was greater than that elicited in mice that survived a virulent infection. S. enterica serovar Typhimurium Dam mutant strains exhibited enhanced sensitivity to med...

Eight preparations of soluble amyloid and degraded amyloid (DAM) were compared immunologically. Unlike amyloid fibrils, six of eight preparations of DAM proved to be relatively strong immunogens. Antisera to DAM reacted weakly or not at all with normal human serum or extracts of normal tissues, but were specifically reactive with amyloid fibrils or DAM. Comparative studies of DAM'S from eight d...

The role of the renal vasculature in eliciting renovascular hypertension (RVH) was established in 1934, when Goldblatt et al. [1] in a classical experimental study demonstrated that partial obstruction of the renal artery increased mean arterial blood pressure (BP). The pathophysiology of renal artery stenosis (RAS) is incompletely understood but has been postulated to be related to increased a...

Construction processes planning and e®ective management are extremely important for success in construction business. Head of a design must be well experienced in initiating, planning, and executing of construction projects. Therefore, proper assessment of design projects' managers is a vital part of construction process. The paper deals with an e®ective methodology that might serve as a decisi...

Urinary tract infections (UTI) are among the most frequently encountered infections in clinical practice globally. Predominantly a burden among female adults and infants, UTIs primarily caused by uropathogenic Escherichia coli (UPEC) results in high morbidity and fiscal health strains. During pathogenesis, colonization of the urinary tract via fimbrial adhesion to mucosal cells is the most crit...