“SEM images were acquired at Frederick Seitz Materials Research Laboratory Central research facilities, UIUC. Funding: We acknowledge University of Illinois at Urbana-Champaign and Children’s Discovery Institute for financial assistance. Authors would like to gratefully acknowledge the kind support from Prof. Gang Logan Liu, ECE, UIUC and his laboratory for allowing us to use his inbuilt maskin...

Fluoresceinated IgG was injected centrally into the rabbit's cornea and both its rate of loss from the tissue and its rate of spread in the stroma were estimated by objective fluorometry. A new technique for determining the rate of loss was established which required only the measurement of the maximum fluorescence in the tissue. The rate at which freshly formed IgG in the blood would arrive at...

In this paper, we study the performance of a testing apparatus that could be used for evaluating the effectiveness of gaseous suppressants and solid fuel retardants under opposed flame spread conditions. A narrow channel, 3 mm in height, 110 mm in width and 375 mm in length, constitutes the most important component of this apparatus. To establish the flow and flame spread parameters in this app...

OBJECTIVE To evaluate the impact and cost-benefit of clinical pharmacist interventions on inappropriate use of prophylactic acid suppressant in hepatobiliary surgical patients in a Chinese tertiary hospital. METHODS A retro-prospective intervention study of patients undergoing elective operations was performed in the Department of Hepatobiliary Surgery of the Affiliated Hospital of Southwest ...

BACKGROUND Proton-pump inhibitors (PPI) and histamine-2 receptor antagonists (H2RA) are common acid suppressants used in gastrointestinal disorders. The trend of usage in Malaysia has changed from predominantly H2RA to PPI from 2007 to 2008, 3.46 versus 2.87 and 2.99 versus 3.24 DDD (Defined Daily Dose)/1000 population/day respectively. This raises concerns as PPI overutilization amounts to hig...

We hypothesized that peptidoglycan (PG) fragments decrease appetite in rats. Male Lewis rats (150 g; n > or = 7) received intraperitoneal (i.p.) injections of purified soluble PG fragments that had been treated with polymyxin B-agarose to remove residual endotoxin. Food consumption and body weight gain were determined at intervals after injection. Single i.p. injections of macromolecular extens...

OBJECTIVES To assess the efficacy and tolerability of lesinurad, an oral selective uric acid reabsorption inhibitor, in combination with allopurinol versus allopurinol alone in patients with gout and an inadequate response to allopurinol. METHODS Patients (N=227) with an inadequate response to allopurinol, defined as serum urate (sUA) ≥6 mg/dL on ≥2 occasions ≥2 weeks apart despite ≥6 weeks o...