introduction : pulmonary adenosquamous carcinoma is an uncommon histological variety of bronchogenic carcinoma, and has histologic areas differentiated as both squamous cell carcinoma and adenocarcinoma and has clinical behavior more like that of adenocarcinoma. tumor stage is higher at the time of diagnosis, and survival is poorer. case presentation : we present a 65 years old woman with bulgi...

cancer starts with a change in one single cell. this change may be initiated by external agents and genetic factors. cancer is a leading cause of death worldwide and accounts for 7.6 million deaths (around 13% of all deaths) in 2008. lung, stomach, liver, colon and breast cancer cause the most cancer deaths each year. in this review, different aspects of gastric cancer; including clinical, path...

In all countries in the world as well Poland, there are no recommendations regarding testing of predictive factors qualifying non-small cell lung cancer (NSCLC) patients for molecularly targ...

nicotine is an alkaloid by high level of addictive property that can quickly assimilate from smoker’s lung. it passes from the placenta and gathers in the developing fetus. our previous study showed that collagen type iv plays a critical role in basement membrane of different embryonic organs. in this study the effect of maternal nicotine was evaluated by collagen iv changes in lung of mice off...

cromolyn sodium, a mast cell stabilizing agent, provides an immediate protective effect against the exercise-induced bronchoconstriction while being used before the exercise. however, cromolyn is ineffective in reversing asthmatic bronchospasm; it is used as a maintenance therapy and has a prophylactic role in chronic asthma.    the purpose of this study was to determine the extent of change in...

(Cell Metabolism 30, 1107–1119.e1–e8; December 3, 2019) As a result of an author oversight in the originally published version this article, example image H&E staining for HKB99 group was accidentally sourced from lung section mice harboring HCC827-Luc, instead HCC827ER9-Luc, when Figure 6F assembled. This error does not affect any results or conclusions paper. The authors sincerely apologize c...

Objective: Lung cancer is a refractory tumor with poor five-year survival rate. Ebracteolatain A (EA), key acetyl-phloroglucinol derived from the traditional Chinese herb Langdu, has been reported to have anti-tumor activity in human breast cancer. However, therapeutic efficacy and underlying mechanism of lung remain be elucidated. In present study, we intended evaluate whether EA exhibits anti...

Although platelets are the cellular mediators of thrombosis, they also immune cells. Platelets interact both directly and indirectly with cells, impacting their activation differentiation, as well all phases response. Megakaryocytes (Mks) cell source circulating platelets, until recently Mks were typically only considered bone marrow–resident (BM-resident) However, platelet-producing reside in ...