نتایج جستجو برای: apl

تعداد نتایج: 3971  

2012
Gerd Gladigau Philipp Haselmayer Inge Scharrer Markus Munder Nadine Prinz Karl Lackner Hansjörg Schild Pamela Stein Markus P. Radsak

The anti-phospholipid syndrome (APS) is characterized by recurrent thrombosis and occurrence of anti-phospholipid antibodies (aPL). aPL are necessary, but not sufficient for the clinical manifestations of APS. Growing evidence suggests a role of innate immune cells, in particular polymorphonuclear neutrophils (PMN) and Toll-like receptors (TLR) to be additionally involved. aPL activate endothel...

Journal: :The Journal of Experimental Medicine 2004
Dmitrii Kamashev Dominique Vitoux Hugues de Thé

PML-RARA was proposed to initiate acute promyelocytic leukemia (APL) through PML-RARA homodimer-triggered repression. Here, we examined the nature of the PML-RARA protein complex and of its DNA targets in APL cells. Using a selection/amplification approach, we demonstrate that PML-RARA targets consist of two AGGTCA elements in an astonishing variety of orientations and spacings, pointing to hig...

Journal: :Journal of anatomy 1995
E van Oudenaarde R A Oostendorp

This study examined the anatomical and functional relationships between the abductor pollicis longus (APL) and the abductor pollicis brevis (APB) muscles. The APL has 2 divisions, a distal superficial division and a more proximal deep one. A direct anatomical connection between the extrinsic and intrinsic muscles of the thumb is made up by the deep division of the APL, the APB and the trapezium...

2004
Aarno Hohti

The APL language is well known for its peculiar symbols which have inhibited the use of this language in many programming environments. Making APL documents of good quality has been difficult and expensive. We describe here a simple way how to use METAFONT to generate an APL font for Tk,X by using existing font definitions as far as possible.

Journal: :Human reproduction update 2015
M Tong C A Viall L W Chamley

BACKGROUND Antiphospholipid antibodies (aPL) are a family of auto-antibodies that are associated with an increased risk of recurrent miscarriage, intrauterine growth restriction and preterm birth. The placenta is a major target of aPL and it is likely that these antibodies promote pregnancy morbidity by affecting trophoblast function. Numerous studies have investigated the effect of aPL on trop...

Journal: :Lupus 1998
M Zeuner R H Straub U Schlosser G Rauh G Schmitz J Schölmerich B Lang

Relapsing polychondritis (RP) is an extremely rare multisystemic disease thought to be of autoimmune origin. In order to assess if RP is associated with anti-phospholipid antibodies (aPL), clinical data and sera of 21 patients with RP were collected in a multicentre study. Concentration of anti-cardiolipin antibodies (aCL) (IgG-, IgM- and IgA-isotypes), anti-phosphatidylserine-antibodies (aPS) ...

2012
Hyun Ji Chun Su Jeong Kim In O Sun Byung Ha Chung Ji-Il Kim In Sung Moon Woo-Sung Min Chul Woo Yang

In general, a 2-yr disease-free duration is recommended before kidney transplantation (KT) in end-stage renal disease (ESRD) patients who also have acute leukemia. However, the optimal disease-free interval has not been specified for all subtypes of acute leukemia. Among these subtypes, acute promyelocytic leukemia (APL) shows a favorable prognosis and low relapse rate compared to other types o...

2011
K W Leong

Acute promyelocytic leukemia (APL) represents 15 % of acute myeloid leukaemia. Prior to tretinoin usage, the treatment of APL was difficult and remission rates were low especially in developing countries due to mortality resulting primarily from bleeding'. APL is associated with a coagulopathy which may be due to a combination of disseminated intravascular coagulation and primary fibrinolysis. ...

2015
Michael Budde

APL is a functional array programming language from the 1960’s. While APL no longer has widespread adoption as a general programming language, there still exist large codebases in APL in the industry. Accelerate is an array language embedded in Haskell for doing high-performance computation on GPU’s. In this report I present a compiler written in Haskell for compiling a typed intermediate array...

2011
E.M. Rego R.H. Jácomo

Distinct epidemiological characteristics have been described in Acute Promielocytic Leukemia (APL). Populations from Latin America have a higher incidence of APL and in some geographic areas a distinct distribution of the PML-RARA isoforms is present. Here, we review the main differences in APL epidemilogy in Latin America as well as treatment outcomes.

نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید