G. gynandra extract was found to potentially diminish the rate of lipid peroxidation, with a significant increase in the levels of enzymatic (superoxide dismutase, catalase and glutathione peroxidase) and non-enzymatic (reduced glutathione vitamins E and C, and uric acid) antioxidants, which were found, altered during aflatoxin B1 (AFB1) injection. The result confirmed that G. gynandra extract ...

The excessive generation of reactive oxygen species (ROS) by abnormal spermatozoa and by contaminating leukocytes has been identified as one of the few defined aetiologies for male infertility. As a consequence, work has begun on evaluating the role of antioxidants in the management of these patients. Glutathione plays a significant role in the antioxidant defences of the spermatogenic epitheli...

BACKGROUND Obesity is associated with increased oxidative stress and lipid peroxidation is thought to play a crucial role in the generation of atherosclerotic lesions of Acute Myocardial Infarction (AMI). METHODS The case-control study contained 120 subjects divided in two groups, 60 patients with AMI and equal number of age- and sex-matched healthy subjects as controls. Ratio of Waist Circum...

The development of granulomatous inflammation with caseous necrosis is an important but poorly understood manifestation of tuberculosis in humans and some animal models. In this study we measured the byproducts of oxidative stress in granulomatous lesions as well as the systemic antioxidant capacity of BCG vaccinated and non-vaccinated guinea pigs experimentally infected with Mycobacterium tube...

Objective: Immunoglobulin A vasculitis (IgAV) is the most common systemic seen in children. The aim of this study to investigate relationship between malondialdehyde-induced oxidative stress, antioxidant system and organ involvement IgAV patients. Method: 32 patients 28 healthy children were included study. Serum malondialdehyde, reduced glutathione, vitamin E, C, retinol, beta-carotene levels ...

Aim: Emerging evidence favors the important role of antioxidants, matrix metalloproteinases (MMPs), and nitric oxide (NO) in the healing of diabetic wounds. There is a lack of substantial evidence regarding the effects of negative pressure on antioxidants, MMPs and NO in chronic wounds associated with diabetes. Methods: A total of 55 type 2 diabetic patients with leg ulcers were divided into 2 ...

Background: The present study was undertaken to estimate the 5’-nucleotidase enzyme in chronic hepatitis B and alcoholics. The oxidative stress, antioxidants and their correlation with 5’-nucleotidase was also included in this study. Methods: The blood samples of 25 subjects (age and sex matched) each from group I (control), group II (alcoholic) and group III (chronic hepatitis B) was taken and...

BACKGROUND The purpose of this study was to verify the effect of whole-body cryotherapy (WBC) in rats on their antioxidant systems, lipid peroxidation products, and their total oxidative status at different exposure times and temperatures. METHODS Antioxidants in serum, plasma, liver, and erythrocytes were evaluated in two study groups following 1 min of exposure to -60°C and -90°C, for 5 and...

as: Hama e Associa Abstract This study was designed to evaluate effect of trigonelline and ethanol extract of Iraqi Fenugreek seeds on oxidative stress in alloxan diabetic rabbits. Oral dose of (10 mg/12 h) isolated trigonelline or (7.7 ml/12 h) of ethanol extract of Iraqi Fenugreek seeds was administered to the rabbits for four weeks. Plasma malondialdehyde (MDA) and glutathione (GSH), as oxid...

Cadmium has been considered a risk factor for humans as it accumulates in body tissues, such as the liver, lungs, kidneys, bones, and reproductive organs. The aim of the present study was to evaluate the effect of Irvingia gabonensis (IG) against cadmium (Cd)-induced nephrotoxicity. The study was performed on twenty (20) male rats divided into four groups: control group, cadmium group (4 mg/kg/...