a series of ortho -hydroxypyridine-4-ones were prepared in high yields and evaluated for antioxidant and iron chelating activities. n 1 -h hydroxypyridinones va , vb , and ve were the best radical scavengers in dpph free radical scavenging assay. compound vb was proved to be the most potent compound in hydrogen peroxide scavenging assay. all of the synthesized compounds had very close chelating...

BACKGROUND Use of antioxidants is a means of reducing rancidity of fats and oils in food stuffs. The commercial synthetic antioxidants in food industry have been suspected to cause negative health effects. Therefore as alternatives, there is a strong need in finding new effective and safe antioxidants from natural sources to prevent deterioration of foods, drugs and cosmetics. OBJECTIVES IN O...

the effect of different solvent systems on the extraction of antioxidant and anti radical agents of grape seed was studied. for this purpose 6 different solvent systems with similar polarity and different selectivity were used to prepare grape seed extract. extraction efficiency, reducing activity, radical scavenging property and the effect of each extract on the increase of thermal resistance ...

One of the most reactive and dangerous agents for the living cells is reactive oxygen free radical species (ROS). When there is an imbalance between ROS generating and scavenging systems (oxidative stress), tissue damages will appear in human body such as degenerative disorders of CNS like Alzheimer's disease. Recently, a high interest in medicinal plants containing antioxidants has been increa...

One of the most reactive and dangerous agents for the living cells is reactive oxygen free radical species (ROS). When there is an imbalance between ROS generating and scavenging systems (oxidative stress), tissue damages will appear in human body such as degenerative disorders of CNS like Alzheimer's disease. Recently, a high interest in medicinal plants containing antioxidants has been increa...

Background: This study was devoted to assessing the inhibitory potential of acetone, methanol, and ethanol extracts of Acroptilon repens against disease-associated enzymes, as well as their antioxidant/antibacterial activity and phytochemical composition. Methods: Comparative assessment using various antioxidant evaluation methods, including ferric reducing antioxidant power, scavenging ability...

Numerous studies have been focused on natural anticarcinogenic agents. Many antioxidants have been identified as anticarcinogens. Antimutagens have also been proposed as cancer chemopreventive agents. The use of natural products as anticancer has a long history that began with traditional medicine. The aim of this study was to evaluate cytotoxicity and antioxidant activity of twenty-three plant...

In search of potent inhibitors cholinesterase enzymes and antioxidant agents, synthetic derivatives dihydroquinazolin-4(1H)-one 1-38 were evaluated as potential anti-Alzheimer agents through in vitro acetylcholinesterase (AChE) butyrylcholinesterase (BChE) inhibitions radical (DPPH ABTS) scavenging activities. The (SAR) was mainly based on the different substituents at aryl part which showed a ...

Background: Mitochondria are a source of reactive oxygen species (ROS), and several natural compounds used as antioxidant agents. This study aimed to investigate compare the effects fresh grape juice red wine on oxidative stress biomarkers in rat liver mitochondria. Materials Methods: In this regard, mitochondria were isolated from 27 male Wistar rats (220-250 g). The cultured different doses f...

The World Health Organization recommends the use of traditional medicines, including herbs, to maintain public health and prevent treat diseases, especially chronic degenerative cancer. Traditional medicine has relatively fewer side effects than modern pharmaceutical medicine. There have been many studies that explore secondary metabolites in plants. Among them, several plant species found anti...