Mutagenic complications can cause disease in both present as well future generations. The disorders are caused by exogenous and endogenous agents that damage DNA beyond the normal repair mechanism. Rapid industrialization population explosion have contributed immensely to changes environment, leading unavoidable exposure mutagens our daily life. As it is impossible prevent exposure, one of bett...

Colorectal Cancer (CRC) is dangerous cancer that causes many cases of death in the world. This spike occurred 2020 with 1.15 million and expected to increase 2040 by 1.92 CRC cases. Some most popular drugs used for chemotherapy are 5-Fluorouracil, Oxaliplatin, Irinotecan. The effects caused using synthetic loss appetite, fatigue, vomiting, numbness, hair loss, low blood cell count. Anthocyanins...

Jackfruit contains high-value biological compounds (HVBC) with important activity in the inhibition of carcinogenesis, through various mechanisms. This study aimed to identify HVBC a methanolic fraction an extract jackfruit; which was reported antimutagenic and antiproliferative against PC3 cells (prostate cancer). The profile includes 3 organic acids, 5 phenolic 12 flavonoids, 2 carotenoids. i...

Natural plant extracts offer a promising hope in the prevention/treatment of cancer arising from genetic mutations. This study evaluated in vitro and in vivo mutagenic and antimutagenic effects of aqueous fraction of Myristica fragrans (AFMF) leaves on TA100 strain of Salmonella typhimurium and Mus musculus (Male Swiss albino mice), respectively. The antioxidant activity of AFMF against 2,2-dip...