Introduction Chronic recurrent multifocal osteomyelitis (CRMO) is a rare autoinflammatory disorder which affects predominantly girls with peak onset between ages of 7 to 12 years. There is a frequent association of CRMO with inflammatory skin or gut disorders. Patients with isolated CRMO are usually treated with nonsteroidal antiinflammatory drugs (NSAIDs) prior to escalation to corticoids and ...

In cultures of mouse or chick embryo ceils several non-steroidal antiinflammatory drugs (salicylates, Ibufenac, phenylbutazone, Indomethacin, flufenamic and mefenamic acids, CI-583, and chloroquine) inhibit the multiplication of various viruses (encephalomyocarditis, Sindbis, influenza A2, Newcastle disease, herpes simplex and vaccinia). Two factors were critical for the virus inhibitory action...

Elke Strehl, Regina Volpert, and Erich F. E lstner Institut für Botanik und Mikrobiologie, Biochemisches Labor, Technische Universität München, Arcisstraße 21, D-80290 München Z. Naturforsch. 49c, 39-43 (1994); received August 16/October 15,1993 Propolis, Dihydrofolate Reductase, Antiinflammatory Drugs, Caffeic Acid Ethanolic and aqueous extracts of the natural compound PROPOLIS indicate substa...

objective: solenostemon monostachyus is used in traditional medicine for the treatment of various ailments such as ulcer, hypertension, pains and inflammatory diseases. evaluation of anti-inflammatory and analgesic activities of s. monostachyus aerial parts was carried out to ascertain its uses in traditional medicine. materials and methods: the aerial parts of s. monostachyus was cold extracte...

Over the past several months clinicians have been confronted at an escalating rate with reports describing the risks of COX-2 inhibitors (coxibs). Information on this class of drugs appears not only in traditional medical journals and textbooks, but also on the Web sites of regulatory agencies, professional societies, and pharmaceutical manufacturers.1–9 An unusual, but noteworthy, aspect of th...