Introduction / objectives Increasing prescription of broad-spectrum antibiotics is regarded to facilitate selection of multiresistant germs. Surveillance of outpatient antibiotic use might contribute to prevent the spread of Methicillin-resistant S. aureus (MRSA) within the EURSAFETY HEALTH-NET. Training sessions on MRSA and antibiotic awareness were offered to general practitioners. A possibil...

Results We identified 75 patients admitted with severe sepsis, with an average age of 75.7 ± 13 years, and an overall hospital mortality of 47%. The patients included had in average 3 severity criteria, mainly acute kidney injury (67%), altered state of consciousness (51%), hypotension (56%), and lactate above 36 mg/dL (34%). Only 31% of the patients received antibiotic treatment in the first 3...

BACKGROUND Antibiotic resistance has been recognized as a worldwide problem. Our aim was to assess the perceptions of Spanish residents about antibiotic use and resistance. METHODS An online cross-sectional survey was conducted on all resident doctors in five teaching hospitals (September to November 2010). A link to the questionnaire was e-mailed to 844 doctors. The questionnaire collected d...

Estimating the amount and cost of excess antibiotic use in ambulatory practice and identifying the conditions that account for most excess use are necessary to guide intervention and policy decisions. Data from the 1998 National Ambulatory Medical Care Survey, a sample survey of United States ambulatory physician practices, was used to estimate primary care office visits and antibiotic prescrip...

To study if antibiotic treatment of outpatients had triggered Clostridium difficile infections (CDI), prescription numbers were compared with CDI-affected patient numbers. A strong correlation was observed for ciprofloxacin (R=0.917), suggesting that increased use of ciprofloxacin by outpatients contributed to increased numbers of CDI. These findings deserve further investigation as they may ha...

OBJECTIVE Antibiotics are commonly recognized as non-indicated for acute bronchitis and upper respiratory tract infection (URI), yet their widespread use persists. Clinical decision support in the form of electronic warnings is hypothesized to prevent non-indicated prescriptions. The purpose of this study was to identify the effect of clinical decision support on a common type of non-indicated ...

Dentistry is a vast domain devoted to managing dental infections as well bolstering and rehabilitating the dentition lost bacterial invasion. Antibiotics are an essential part of dentistry its relative specialties, prescribing antibiotics privilege that should not be abused. Antibiotic prescriptions in relatively small but nonetheless significant. With emergence antibiotic-resistant species, th...

BACKGROUND Antibiotic overuse is of great public health concern. This study assessed whether intervention among physicians and their treated population could achieve a sustained reduction in antibiotic use, specifically in classes known to promote antibiotic resistance among children in a community setting. METHODS We performed a cluster randomized controlled multifaceted trial among 52 prima...

OBJECTIVES To optimize empirical treatment of urinary tract infections (UTIs), regular evaluation of the antibiotic susceptibility of the most common uropathogen, Escherichia coli, is necessary. We compared the antibiotic prescription rate for UTIs in women and the E. coli antibiotic susceptibility results, including the prevalence of extended-spectrum β-lactamase (ESBL)-producing strains, in 2...