نتایج جستجو برای: anti epileptogenic

تعداد نتایج: 364581  

Journal: :Revista brasileira de psiquiatria 2004
Ricardo Guarnieri Jaime Eduardo Cecílio Hallak Roger Walz Tonicarlo Rodrigues Velasco Veriano Alexandre Júnior Vera Cristina Terra-Bustamante Lauro Wichert-Ana Américo Ceiki Sakamoto

Epilepsy is one of the main causes of functional disability, and it is usually associated to psychiatric comorbidity, such as psychosis of epilepsy (POE). POE requires more careful pharmacological treatment, considering the propensity of the antipsychotics (AP) to provoke seizures and the risk of pharmacokinetic interaction with anti-epileptic drugs (AEDs). We discussed the classification and t...

Journal: :Neuropharmacology 2013
Annamaria Vezzani Alon Friedman Raymond J Dingledine

One compelling challenge in the therapy of epilepsy is to develop anti-epileptogenic drugs with an impact on the disease progression. The search for novel targets has focused recently on brain inflammation since this phenomenon appears to be an integral part of the diseased hyperexcitable brain tissue from which spontaneous and recurrent seizures originate. Although the contribution of specific...

Journal: :Brain : a journal of neurology 2005
Warren T Blume Samuel Wiebe Lisa M Tapsell

This study compares ictal semiology, neurological examination and scalp EEG between lateral and mesial occipital epilepsy to assess the contribution non-invasive data make in determining the epileptogenic region within an occipital lobe. We assessed seizure origin in 41 occipital patients as lateral (11 patients), mesial (20) and both surfaces (10) as indicated by subdurally recorded seizures (...

Journal: :BMC Neurology 2007
Ross P Carne Terence J O'Brien Christine J Kilpatrick Lachlan R MacGregor Lucas Litewka Rodney J Hicks Mark J Cook

BACKGROUND 'MRI negative PET positive temporal lobe epilepsy' represents a substantial minority of temporal lobe epilepsy (TLE). Clinicopathological and qualitative imaging differences from mesial temporal lobe epilepsy are reported. We aimed to compare TLE with hippocampal sclerosis (HS+ve) and non lesional TLE without HS (HS-ve) on MRI, with respect to quantitative FDG-PET and MRI measures. ...

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