نتایج جستجو برای: anthrax spore

تعداد نتایج: 13072  

Journal: :PLoS Computational Biology 2009
Judith Legrand Joseph R. Egan Ian M. Hall Simon Cauchemez Steve Leach Neil M. Ferguson

Rapidly identifying the features of a covert release of an agent such as anthrax could help to inform the planning of public health mitigation strategies. Previous studies have sought to estimate the time and size of a bioterror attack based on the symptomatic onset dates of early cases. We extend the scope of these methods by proposing a method for characterizing the time, strength, and also t...

2013
Antonio Fasanella

Editorial Anthrax is a non-contagious infectious disease that affects a wide range of animal species, including humans, but especially sensitive are domestic and wild ruminants. The bacterial agent is Bacillus anthracis, whose main feature is to form spores that can survive in the environment for several decades. Anthrax, in susceptible animals, has a generally fatal outcome characterized by su...

2016
A. D. Stewart

comes infected during the operation of skinning and cutting up .the animal, which has died of anthrax. The bacilli in the blood and organs, on exposure to air immediately spore and the hair of the hide becoming soiled with the blood and discharges becomes intensely infected with spores. Unless the hair is very thoroughly washed and disinfected, these spores remain on the hairs duringthe process...

Journal: :PLoS Pathogens 2007
Benoit Raymond Dominique Leduc Lucas Ravaux Ronan Le Goffic Thomas Candela Michel Raymondjean Pierre Louis Goossens Lhousseine Touqui

Bacillus anthracis, the etiological agent of anthrax, is a spore-forming gram-positive bacterium. Infection with this pathogen results in multisystem dysfunction and death. The pathogenicity of B. anthracis is due to the production of virulence factors, including edema toxin (ET). Recently, we established the protective role of type-IIA secreted phospholipase A2 (sPLA2-IIA) against B. anthracis...

Journal: :Journal of immunology 2005
Katherine C Brittingham Gordon Ruthel Rekha G Panchal Claudette L Fuller Wilson J Ribot Timothy A Hoover Howard A Young Arthur O Anderson Sina Bavari

Phagocytosis of inhaled Bacillus anthracis spores and subsequent trafficking to lymph nodes are decisive events in the progression of inhalational anthrax because they initiate germination and dissemination of spores. Found in high frequency throughout the respiratory track, dendritic cells (DCs) routinely take up foreign particles and migrate to lymph nodes. However, the participation of DCs i...

Journal: :Infection and immunity 2004
Hadar Marcus Rachel Danieli Eyal Epstein Baruch Velan Avigdor Shafferman Shaul Reuveny

Protective antigen (PA)-based vaccination is an effective countermeasure to anthrax infection. While neutralizing anti-PA antibody titers elicited by this vaccine serve as good correlates for protection against anthrax (S. Reuveny, M. D. White, Y. Y. Adar, Y. Kafri, Z. Altboum, Y. Gozes, D. Kobiler, A. Shafferman, and B. Velan, Infect. Immun. 69:2888-2893, 2001), no data are available on the co...

Journal: :PLoS ONE 2007
Matthew N. Van Ert W. Ryan Easterday Lynn Y. Huynh Richard T. Okinaka Martin E. Hugh-Jones Jacques Ravel Shaylan R. Zanecki Talima Pearson Tatum S. Simonson Jana M. U'Ren Sergey M. Kachur Rebecca R. Leadem-Dougherty Shane D. Rhoton Guenevier Zinser Jason Farlow Pamala R. Coker Kimothy L. Smith Bingxiang Wang Leo J. Kenefic Claire M. Fraser-Liggett David M. Wagner Paul Keim

Anthrax, caused by the bacterium Bacillus anthracis, is a disease of historical and current importance that is found throughout the world. The basis of its historical transmission is anecdotal and its true global population structure has remained largely cryptic. Seven diverse B. anthracis strains were whole-genome sequenced to identify rare single nucleotide polymorphisms (SNPs), followed by p...

2016
Theodor Chitlaru Ma’ayan Israeli Erez Bar-Haim Uri Elia Shahar Rotem Sharon Ehrlich Ofer Cohen Avigdor Shafferman

Anthrax is a lethal disease caused by the gram-positive spore-producing bacterium Bacillus anthracis. Live attenuated vaccines, such as the nonencapsulated Sterne strain, do not meet the safety standards mandated for human use in the Western world and are approved for veterinary purposes only. Here we demonstrate that disrupting the htrA gene, encoding the chaperone/protease HtrA (High Temperat...

Journal: :Journal of istanbul veterinary sciences 2021

Live spore Sterne 34F-2 strain of Bacillus anthracis vaccine is being used to control anthrax disease in Bangladesh. After produced this Livestock Research Institute (LRI) under the Department Services (DLS), it distributed at farmers level through district and Upazila Offices. In these distribution pathways, has been transported stored for a few days each station. The present study was carried...

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