There is a peculiarity in the articulation of the two parietal bones with the frontal bone at the top of the skull. The anterior border of the parietal bone is deeply serrated and is bevelled at the expense of the outer surface above and of the inner below. The border of the vertical portion of the frontal bone is thick, strongly serrated, bevelled at the expense of the internal table above, wh...

Drosophila Hedgehog (Hh) is secreted by Posterior (P) compartment cells and induces Anterior (A) cells to create a developmental organizer at the AP compartment border. Hh signaling converts Fused (Fu) to a hyperphosphorylated form, Fu*. We show that A border cells of wing imaginal discs contain Fu*. Unexpectedly, P cells also produce Fu*, in a Hh-dependent and Ptc-independent manner. Increasin...

Introduction Axillary artery begins as a continuation of 3rd part of subclavian artery at the outer border of the first rib. It extends at the lower border of teres major muscle where it continues as the brachial artery. The pectoralis minor muscle divides the axillary artery into three parts. It usually gives off 6 branches. The 1st part which is medial to pectoralis minor muscle gives superio...

Radiologic evaluation of basal foramina of the skull is frequently a critical aspect in the diagnosis of patients with deficits referable to cranial nerves. Commonly encountered normal asymmetries and individual variations often make interpretation difficult. A pseudoforamen in the skull base was initially observed in skull radiographs of several patients and correlated with images of a dried s...

BACKGROUND Thyroid cartilage is an important barrier in anterior cervical approach surgery. The objective of this study is to establish normative values for thyroid cartilage at three planes and to determine their significance on preoperative positioning and intraoperative traction in surgery via the anterior cervical approach. METHODS Neck CT scans were collected from 600 healthy adults who ...

We studied the refractoriness of Purkinje fibers with the intent of localizing critical sites of block of premature impulses. To preserve the ventricular conducting system (VCS) nearly intact in vitro, we used a modification of the Elizari preparation. This was superfused with a physiologic salt solution. Action potential durations increased progressively from the His bundle to the distal Purki...

The ability of the anterior apical ectodermal ridge to promote outgrowth in the chick wing bud when disconnected from posterior apical ridge was examined by rotating the posterior portion of the stage-19/20 to stage-21 wing bud around its anteroposterior axis. This permitted contact between the anterior and posterior mesoderm, without removing wing bud tissue. In a small but significant number ...

BACKGROUND AND PURPOSE Anatomic imaging of patients with chronic well-treated hypertension has demonstrated dilatation of the lateral cerebral ventricles and left brain atrophy, whereas positron emission tomography has shown only subtle reductions in regional cerebral metabolic rates for glucose in some subcortical nuclei. To further explore the implications of the imaging changes, an analytic ...

We report here the complete genome sequences of three border disease virus (BDV) strains of the same subgenotype isolated in Switzerland from a sheep, a cow, and a pig, respectively. This is the first report of full-length sequences of a tentatively new subgenotype isolated from three different species of cloven-hoofed farm animals.

Upstream regulatory sequences that control gene expression evolve rapidly, yet the expression patterns and functions of most genes are typically conserved. To address this paradox, we have reconstructed computationally and resurrected in vivo the cis-regulatory regions of the ancestral Drosophila eve stripe 2 element and evaluated its evolution using a mathematical model of promoter function. O...