Polycystic ovary syndrome, with an incidence of up to 10%, is one the communal causes anovulation in females reproductive age. Diagnostic criteria for PCOS include enlarged polycystic ovaries, obesity, hirsutism, and oligomenorrhea. These women are more susceptible endometrial cancer, type II diabetes, dyslipidemia premature atherosclerosis. Objective: The aim this study was determine different...

Clinical Course Young women of reproductive age most frequently seek attention initially because of irregular menses, hirsutism, or infertility, but PCOS has a long prodrome with detectable abnormalities throughout the life cycle of affected women. The earliest manifestations of PCOS are discernible in the peripubertal years. Ovarian hyperandrogenism and insulin resistance develop with increase...

Polycystic ovary syndrome (PCOS) is the most prevalent cause of anovulatory infertility in women in the reproductive age with a prevalence rate of about 10% [1]. PCOS is characterized by both metabolic and reproductive abnormalities. According to Rotterdam criteria (2004), the patient should be diagnosed to have PCOS when two of the following are met: chronic oligoovulation or anovulation, clin...

Anovulatory cycles are a symptom and not a disease. Polycystic ovary syndrome, pituitary microadenoma, impaired GnRH release, and hypothyroidism are common etiologies for anovulation and should be excluded. Patients can present with amenorrhea which needs etiology-specific treatment or with acute dysfunctional uterine bleeding which might need emergency treatment. Emergency treatment can be eit...

During the transitioning through puberty, adolescents present with varied gynaecological issues, among which puberty menorrhagia is a significant complaint. The most common underlying cause of puberty menorrhagia is anovulation, other causes being endocrine dysfunction, PCOS and bleeding disorders. Congenital prothrombin deficiency is an extremely rare inherited coagulopathy, affecting one in t...

Dunaliella salina, lycopene and vitamin A Carotenoids especially betacarotene, vitamin A and lycopene have been shown to boost sperm parameters [2-5] Dunaliella salina is a microalgae which is a naturally rich source of mixed carotenoids including lycopene [6] Betacarotene, lycopene and vitamin A can reduce sperm DNA fragmentation and lipid peroxidation [1, 2] Vitamin A is an essential nutrient...

Metformin alone compared with placebo increases the ovulation rate in women with polycystic ovary syndrome (PCOS) but should not be used as first-line therapy for anovulation because oral ovulation induction agents such as clomiphene citrate or letrozole alone are much more effective in increasing ovulation, pregnancy, and live-birth rates in women with PCOS. There is fair evidence that metform...

This global overweight and obesity epidemics has become one of the largest public health problem worldwide and is increasingly more common among women in reproductive age. Along with the prevalence of overweight women, there is an increase in women with anovulatory infertility. Thus, we carried out a bibliographic research in the PubMed, Lilacs and SciELO databases, using the combinations in Po...

The alpha-fetoprotein gene (Afp) is a member of a multigenic family that comprises the related genes encoding albumin, alpha-albumin, and vitamin D binding protein. The biological role of this major embryonic serum protein is unknown although numerous speculations have been made. We have used gene targeting to show that AFP is not required for embryonic development. AFP null embryos develop nor...

Submit Manuscript | http://medcraveonline.com Abbrevations: PCOS: Polycystic Ovary Syndrome; OCPs: Oral Contraceptive Pills; HA: Hyper androgenic Anovulation; SHBG: Sex-Hormone Binding Globulin; LDL: Low-Density Lipoprotein; HDL: High-Density Lipoprotein; HTN: Hypertension; AR: Androgen Receptor; LH: Luteinizing Hormone; VNTR: Variable Number of Tandem Repeats; TNF-alpha: Tumor Necrosis Factora...