نتایج جستجو برای: annexin v

تعداد نتایج: 306698  

Journal: :Circulation research 2013
Sophie E P New Claudia Goettsch Masanori Aikawa Julio F Marchini Manabu Shibasaki Katsumi Yabusaki Peter Libby Catherine M Shanahan Kevin Croce Elena Aikawa

RATIONALE We previously showed that early calcification of atherosclerotic plaques associates with macrophage accumulation. Chronic renal disease and mineral imbalance accelerate calcification and the subsequent release of matrix vesicles (MVs), precursors of microcalcification. OBJECTIVE We tested the hypothesis that macrophage-derived MVs contribute directly to microcalcification. METHODS...

Mahdi Zahedpanah, Mahin Nikugoftar, Mohsen Nikbakht, Mojgan Shaiegan, Saeed Mohammadi, Seyed Hamidollah Ghaffari,

Background: Interfering with cell proliferation and survival is a critical role for antineoplastic drugs leading to cell death through induction of apoptosis. Alternative treatments with herbal extracts offer insights into acute myeloid leukemia (AML) therapy. Parthenolide (PTL), an extract from feverfew, induces apoptosis in primary human leukemia stem cells (LSCs) and bulk leukemic cell popul...

Journal: :Clinical Medicine Insights: Reproductive Health 2010

Journal: :Mechanisms of Development 2001
Bent Brachvogel Heike Welzel Helga Moch Klaus von der Mark Clementine Hofmann Ernst Pöschl

Annexin A5 (annexin V, anchorin CII) represents the prototype member of the large annexin family, characterized by its ability to interact with phospholipids in a calcium-dependent manner and to form calcium-specific ion channels. Despite intense biochemical analysis, the in vivo expression and function of this annexin during mouse development, still remains unclear. Immunohistochemistry, in si...

2013
Runa H Poulsen Jan T Rasmussen June Anita Ejlersen Christian Flø Lise Falborg Christian W Heegaard Michael Rehling

BACKGROUND Phosphatidylserine (PS) is a phospholipid normally located in the inner leaflet of the cell membrane. PS is translocated from the inner to the outer leaflet of the plasma membrane during the early stages of apoptosis and in necrosis. In cell and animal studies, reversible PS externalisation to the outer membrane leaflet has been observed in viable cells. Hence, PS markers have been p...

2013
Runa H Poulsen Jan T Rasmussen June Anita Ejlersen Christian Flø Lise Falborg Christian W Heegaard Michael Rehling

Background: Phosphatidylserine (PS) is a phospholipid normally located in the inner leaflet of the cell membrane. PS is translocated from the inner to the outer leaflet of the plasma membrane during the early stages of apoptosis and in necrosis. In cell and animal studies, reversible PS externalisation to the outer membrane leaflet has been observed in viable cells. Hence, PS markers have been ...

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