In the title complex, [Ag(NO(3))(C(5)H(5)NO)](n), the Ag(I) atom is coordinated by two O atoms from two different 4-pyridone ligands and two O atoms from one nitrate anion, displaying a nearly planar coordination geometry. The O atoms of two 4-pyridone ligands bridge two symmetrically related AgNO(3) units, forming a dimer, with an Ag⋯Ag separation of 3.680 (2) Å. Neighbouring dimers are linked...

Purpose: A high anion gap (AG) is known to be a significant risk factor for serious acid-base imbalances and death in acute poisoning cases. The strong ion difference (SID), or (SIG), has recently been used predict in-hospital mortality kidney injury (AKI) patients with systemic inflammatory response syndrome. This study presents comprehensive analysis order identify the predictive value of SIG...

Although the metabolism and disposition of diclofenac (DF) has been studied extensively, information regarding the plasma levels of its acyl-β-d-glucuronide (DF-AG), a major metabolite, in human subjects is limited. Therefore, DF-AG concentrations were determined in plasma (acidified blood derived) of six healthy volunteers following a single oral DF dose (50 mg). Levels of DF-AG in plasma were...

When intracellular chloride activity (aiCl) was monitored with chloride-sensitive liquid ion exchanges (CLIX) microelectrodes in Balanus photoreceptors, replacement of extracellular chloride (Cl0) by methanesulfonate or glutamate was followed by a rapid but incomplete loss of aiCl. When propionate was used as the extracellular anion substitute, CLIX electrodes detected an apparent gain in aiCl,...

The synthesis of a simple ambidentate ligand 1-(3-methylsulfanyl-phenyl)-3-pyridin-2-yl-urea (L) capable of binding metal ions via a pyridyl nitrogen atom or thioether sulfur donor is reported. The pyridyl functionality is located adjacent to an anion binding urea group allowing this region of the ligand to bind contact ion-pairs by simultaneous coordination and hydrogen bonding interactions. T...

Genomic alignments of sequenced cellular messenger RNA contain gapped alignments which are interpreted as consequence of intron removal. The resulting gap-sites, genomic locations of alignment gaps, are landmarks representing potential splice-sites. As alignment algorithms report gap-sites with a considerable false discovery rate, validations are required. We describe two quality scores, gap qu...

The asymmetric unit of the title compound, {[AgL]·BF4·0.5CH3OH} n , L = N-(pyridin-4-ylmeth-yl)pyridine-3-amine, C11H11N3, contains one Ag(I) ion, one ligand L, one tetra-fluorido-borate anion disordered over two orientations in a 0.669 (13):0.331 (13) ratio and one half of a methanol solvent mol-ecule situated on an inversion center. Each Ag(I) ion is coordinated by two N atoms from two L liga...

While acid-base disturbances are known to occur with chronic pancreatitis, few cases have been reported in which non-anion gap metabolic acidosis is caused by pancreaticopleural fistula, a known complication of chronic pancreatitis. The current report describes the case of a 49-year-old African American woman who presented with severe pleuritic chest pain and dyspnea at rest. The patient had a ...