BACKGROUND Medication errors are common, life threatening, costly but preventable. Information technology and automated systems are highly efficient for preventing medication errors and therefore widely employed in hospital settings. The aim of this study was to construct a probabilistic model that can reduce medication errors by identifying uncommon or rare associations between medications and...

Background Between 2000 and 2010, the consumption of antibiotics in 71 countries increased by 36% [1]. The rise of antibiotic consumption is expected to continue, considering the potential genetic mutation of super bacteria. Most antibiotics cannot be fully metabolised by the human body [2] and are excreted into the environment via wastewater effluents. Typical biological treatment processes, w...

More and more software projects are using COTS (commercial-off-the-shelf) components. One of the most challenging problems in COTS-based development is to evolve a system to follow changes in the customer requirements. It is therefore important to increase the changeability of the COTS-based system, so that new component can easily replace the problematic COTS components. Aspect-Oriented Progra...

A lot of different composition mechanisms claim to permit aspect-oriented software development because they are able to handle the problem of tangled code which was the original target of aspect-oriented programming (AOP). However, it becomes hard to compare those different approaches, because they usually focus on different kinds of tangled code. For comparing different approaches it is necess...

Ferrous ion-based catalysts have been widely employed to oxidatively destruct the major industrial pollutants such as phenolic compounds through advanced oxidation processes (AOPs). These agents, however, inevitably show several drawbacks including the need for pH adjustment and further purification steps to remove residual salts. Here we report the use of a chemical vapour deposition (CVD) gra...

Sequential helminth egg inactivation using a solar driven advanced oxidation process (AOP) followed by chlorine was achieved. The photo-assisted Fenton process was tested alone under different H(2)O(2) and/or Fe(II) concentrations to assess its ability to inactivate Ascaris suum eggs. The effect of free chlorine alone was also tested. The lowest egg inactivation results were found using Fe(II) ...

Bilateral paramedian thalamic stroke is a special ischemic pattern that results from occlusion of the artery of Percheron (AOP), a rare anatomic variant of the paramedian arteries. We report a case of bilateral thalamic infarctions, with a dramatic improvement after thrombolysis. DSA demonstrated recanalization of AOP with possible unreported variation.

Antioxidant potential (AOP) is not only the property of the matrix analyzed but also depends greatly on the methodology used. The chromogenic radicals 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS•+), 2,2-diphenyl-1-picrylhydrazyl (DPPH•) and Folin-Ciocalteu (FC) assay were applied to estimate how the method and the composition of the assay solvent influence the AOP determined fo...

Although aspect-oriented programming originally emerged to overcome fundamental modularity problems in object-oriented applications, its ideas have long been backported to legacy languages like Cobol, C, . . . As systems written in these languages are prime targets for re(verse)-engineering efforts, aspects can now be used for these purposes. Before applying dynamic analysis techniques on an in...

The purpose of this paper is to assess the advantages and disadvantages of a state of the art programming paradigm, called Aspect Oriented Programming (AOP for short) for building component-based systems. For the purposes of this comparison, several other approaches based on the AOP methodology will be examined, in matters of efficiency, ease of programming, robustness, and other important metr...