Introduction: Sambiloto (Andrographis paniculata) is an antidiabetic medicinal plant that acts by inhibiting the ?-amylase enzyme. Andrographolide, active compound of sambiloto leaf, insoluble in water but dissolves ethanol. Aim: This study compared vitro activity aqueous extract and ethanolic leaf with Methods: The inhibitory test enzyme was carried out using ultraviolet-visible spectrophotome...

Herbal utilization, as an antidiabetes agent, is interesting topic to find acceptable herbal drugs decrease blood glucose levels. The aim of this review evaluate the potency selected medicines reduce levels and identify chemical compounds responsible for reducing glucose. mechanisms action different used might be also different. reduction by Aloe vera, Andrographis paniculata, Trigonella foenum...

Background: Associated with sepsis is the illness known as acute kidney injury (AKI). AKI may be mediated by uric acid, and blood creatinine levels can utilized to diagnose condition measure function. Sambiloto (Andrographis paniculata) a traditional medicine that has flavonoid compounds reduce Xanthine Oxidase Inhibitors which acid levels.Objective: Septic model rats generated lipopolysacchari...

Medicinal herbs are significant source of pharmaceutical drugs. Latest trends have shown increasing demand of phytodrugs and some medicinal herbs have proven hepatotprotective potential. Silymarin, a flavonol lignan mixture) extracted from the Silybum marianum (milk thistle) is a popular remedy for hepatic diseases. Today every herbal company is marketing formulations for liver disorders but th...

Andrographolide (AND), the diterpene lactone compound, was purified by HPLC from the methanolic fraction of the plant Andrographis paniculata. The compound was found to have potent antiplasmodial activity when tested in isolation and in combination with curcumin and artesunate against the erythrocytic stages of Plasmodium falciparum in vitro and Plasmodium berghei ANKA in vivo. IC(50)s for arte...