metronidazole and its derivatives have both antiprotozoal and anti bacterial effects. the reproductive toxicity of metronidazole has been observed in some studies. the aim of this study was to determine the detrimental effects of metronidazole on spermatogenesis and testicular androgenesis in male adult rats. eighteen male wistar rats (70-90 days old) were randomly divided into three groups. an...

Haploid microspore-derived embryos (MDEs) of wheat were obtained by in vitro androgenesis. These  embryos were employed to evaluate the transient expression of GUS gene (uidA) following particle bombardment. Using the Bio-Rad PDS-1000/He system, the physical parameters including rupture disk pressure (900, 1100 and 1350 psi); microprojectile travel distance (6 and 9 cm); gold particles size (0....

BACKGROUND AND AIMS Cassava (Manihot esculenta), a major food staple in the tropics and subtropics, thrives even in environments undergoing threatening climate change. To satisfy the increasing demand for crop improvement and overcome the limitations of conventional breeding, the introduction of inbreeding techniques such as the production of doubled haploid lines via androgenesis or gynogenesi...

Objective: The present study was to evaluate the dose-dependent effects of Cuminum cyminum (C. cyminum) on testicular gametogenic and androgenic activities in adult rat. Methods: The hydro-methanolic extract was administered orally at the dose of 30mg, 60mg and 120mg/100g body weight of rats for 28 days. The effects of the treatment on reproductive organs and testicular steroidogenesis were inv...

Anther culture is one of the most popular methods for obtaining haploid triticale plants. The current paper has presented study results efficiency method plants in promising winter forms bred by Federal Agricultural Research Center South-East. There been estimated haploproduction parameters studied genotypes on nutrient media C-17 and P-2. were no unresponsive to androgenesis. found that medium...

I T is generally accepted at present that during cleavage in echinoderms, amphibians, and fishes, the nuclei do not have specific functions in regulating development, their role being at this time restricted to participation in the processes of cleavage (Schechtman & Nishihara, 1955). Eggs devoid of nuclei sometimes begin cleavage which may proceed up to the stage of the late blastula. Extirpat...

Gametes have the unique potential to enter the sporophytic pathway, called androgenesis. The plants produced are usually haploid and recombinant due to the preceding meiosis and they can double their chromosome number to form doubled haploids, which are completely homozygous. Availability of the doubled haploids facilitates mapping the genes of agronomically important traits, shortening the tim...

Segregation distorters are curious, evolutionarily selfish genetic elements, which distort Mendelian segregation in their favor at the expense of others. Those agents include gametocidal factors (Gc), which ensure their preferential transmission by triggering damages in cells lacking them via chromosome break induction. Hence, we hypothesized that the gametocidal system can be adapted for chrom...

This study tested the hypothesis that nitric oxide (NO) inhibits the rate-limiting catalytic step in steroidogenesis, cytochrome P450 cholesterol side-chain cleaving enzyme (CYP11A1), independent of soluble guanylyl cyclase (GC-S) stimulation. To assess CYP11A1 activity, pregnenolone levels were quantified in murine adrenocortical Y1 cells in the presence of the 3beta-hydroxy-Delta(5)-steroid d...