We report the case of a 66-year-old woman with tumor-induced osteomalacia (TIO) caused by fibroblast growth factor 23 (FGF-23) secreting mesenchymal tumor localized in a lumbar vertebra and review other cases localized to the axial skeleton. She presented with nontraumatic low back pain and spontaneous bilateral femur fractures. Laboratory testing was remarkable for low serum phosphorus, phosph...

Hepatocellular adenoma is an uncommon neoplasm, especially in the childhood age group. We describe a previously obese 13-year-old male with a giant hepatocellular adenoma requiring an extensive hepatic resection. The related pediatric tumor literature, diagnosis and clinical management is discussed.

primitive neuroectodermal tumor (pnet) is usually an aggressive, rapidly progressing and metastasizing tumor. occurrence of this type of tumor in the kidney is considered as unusual and few cases have been reported so far. we present a metastatic pnet arising probably from the kidney in a 17-year-old female patient with local invasion and metastasis to the stomach. pnet should be considered as ...

intraocular metastatic tumors have been increasingly reported in the recent past. unlike choroidal metastasis, metastasis to retina is very rare and so far has been reported in very few case reports only. case presentation : a 56 year-old male who presented with a history of adenocarcinoma of the cecum and underwent lap colectomy for the primary cecal tumor, received adjuvant chemotherapy for a...

Idiopathic pulmonary fibrosis (IPF) is a fatal interstitial lung disease characterized by chronic, progressive, and fibrotic injury. Although remarkable progress has been made toward understanding the pathogenesis of PF, finding more effective treatments for this remains challenge. In study, we describe an innovative macrophage-based approach to deliver anti-fibrotic protein inhibit PF in mouse...

difficult diagnosis in endocrinology, gynecology, and reproductive medicine. to help solve this issue, the rotterdam consensus conference proposed to include the ultrasonographic follicle count as a new diagnostic criterion, in addition to hyperandrogenism and oligo-anovulation. unfortunately, its assessment does not offer sufficient reliability worldwide. objective: to explore the possible rol...

Maternal testosterone has been indicated to affect sex ratio of offspring. The present study was conducted to elucidate the role of androgen receptor in this regard by blockade of androgen receptor using flutamide in female mice. Mice were randomly assigned to two experimental groups. Mice in the control (n = 20) and treatment (n = 20) groups received 8 IU equine chorionic gonadotropin (eCG) fo...

A solid pseudopapillary neoplasm of the pancreas is a rare pancreatic tumor with a low malignant potential. It typically occurs in young women. Solid pseudopapillary neoplasm associated with extra-pancreatic and pancreatic anomalies are occasionally reported. We report a case of an solid pseudopapillary neoplasm with a concomitant variation of the common hepatic artery in a 43-year-old woman. T...

Objective: The scientific community has recently directed its attention towards investigating the role of androgens in female sexuality. This narrative review aims to elucidate central and peripheral androgen-mediated mechanisms involved sexual health function. Additionally, current state androgen therapeutic options is discussed. Mechanism: We searched several literature databases, including E...

Colorectal masses can be non-neoplasm, benign neoplasm and malignant neoplasm. Diagnosis of colorectal mass done by biopsy or surgery then followed histopathological examination. The aim this study was to described the histopathology feature in Anatomic Pathology Laboratory Arifin Achmad Regional Hospital Riau Province January 2015 - December 2019. This found 304 cases consisted men (55,6%) wom...